Results 81 to 90 of about 8,764 (251)
Advanced Science, EarlyView.When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Increasing genomic prediction accuracy for unphenotyped full-sib families by modeling additive and dominance effects with large datasets in white spruce. [PDF]
Front Plant Sci, 2023 Nadeau S +5 more
europepmc +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Genetic parameters and selection in full-sib families of tall fescue using best linear unbiased prediction (BLUP) analysis. [PDF]
BMC Plant Biol, 2022 Pirnajmedin F +3 more
europepmc +1 more source
Genome-wide association study comparison analysis based on Hanwoo full-sib family
Animal BioscienceObjective: The improvement of carcass traits is essential for the Hanwoo industry because of the Hanwoo grade determination system, and genome-wide association study (GWAS) analysis is an instrumental tool for identifying the genetic factors that impact these traits. While GWAS analysis utilizing family data offers advantages in minimizing genetic bias,
Ji-Yeong Kim +5 more
openaire +3 more sources
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Advanced Science, EarlyView.Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Genetic gain for grain yield and popping expansion in full-sib recurrent selection in popcorn
Crop Breeding and Applied Biotechnology, 2002 A first cycle of full-sib recurrent selection was conducted in a popcorn base population, with the objective of improving popping expansion and grain yield as recommended in a previous study by Pereira and Amaral Júnior (2001).
Máskio Daros +2 more
doaj
Advanced Science, EarlyView.This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou +8 more
wiley +1 more source
Methods for the detection of multiple linked QTL applied to a mixture of full and half sib families
Genetics Selection Evolution, 2007 A new multiple trait strategy based on discriminant analysis was studied for efficient detection of linked QTL in outbred sib families, in comparison with a multivariate likelihood technique.
Le Roy Pascale, Gilbert Hélène
doaj +1 more source
Advanced Science, EarlyView.Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su +13 more
wiley +1 more source