Results 81 to 90 of about 987,581 (290)

Matrix-State Particle Filter for Wishart Stochastic Volatility Processes [PDF]

open access: yes
This work deals with multivariate stochastic volatility models, which account for a time-varying variance-covariance structure of the observable variables.
Domenico Sartore, Roberto Casarin
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Missing signposts on the roadmap to quality: a call to improve medication adherence indicators in data collection for population research

open access: yesFrontiers in Pharmacology, 2013
Purpose: Poor adherence to prescribed medicines is associated with increased rates of poor outcomes, including hospitalization, serious adverse events, and death, and is also associated with increased healthcare costs.
Bradi B. Granger   +9 more
doaj   +1 more source

Shannon-R\'enyi entropies and participation spectra across 3d $O(3)$ criticality

open access: yes, 2014
Universal features in the scalings of Shannon-R\'enyi entropies of many-body groundstates are studied for interacting spin-$\frac{1}{2}$ systems across (2+1) dimensional $O(3)$ critical points, using quantum Monte Carlo simulations on dimerized and ...
Alet, Fabien   +2 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Connecting the latent multinomial

open access: yes, 2015
Link et al. (2010) define a general framework for analyzing capture-recapture data with potential misidentifications. In this framework, the observed vector of counts, $y$, is considered as a linear function of a vector of latent counts, $x$, such that ...
Bonner, Simon J., Schofield, Matthew R.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Wavefront shaping simulations with augmented partial factorization

open access: yesJPhys Photonics
Wavefront shaping can tailor multipath interference to control multiple scattering of waves in complex optical systems. However, full-wave simulations that capture multiple scattering are computationally demanding given the large system size and the ...
Ho-Chun Lin, Zeyu Wang, Chia Wei Hsu
doaj   +1 more source

Assessment of relationships between pigs based on pedigree and genomic information

open access: yesAnimal, 2020
Relationships play a very important role in studies on quantitative genetics. In traditional breeding, pedigree records are used to establish relationships between animals; while this kind of relationship actually represents one kind of relatedness, it ...
J. Zhang, H. Song, Q. Zhang, X. Ding
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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