Results 71 to 80 of about 5,701,734 (271)

Constraint capture and maintenance in engineering design [PDF]

, 2008
The Designers' Workbench is a system, developed by the Advanced Knowledge Technologies (AKT) consortium to support designers in large organizations, such as Rolls-Royce, to ensure that the design is consistent with the specification for the particular ...
Fowler, David W, Ajit, Suraj, Knott, David, Sleeman, Derek   +3 more
core   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

PEBAX-based mixed matrix membranes for post-combustion carbon capture [PDF]

, 2018
Polymeric membranes exhibit a trade-off between permeability and selectivity in gas separations which limits their viability as an economically feasible post-combustion carbon capture technology.
Bryan, Nicholas James
core   +3 more sources

Wavefront shaping simulations with augmented partial factorization

JPhys Photonics
Wavefront shaping can tailor multipath interference to control multiple scattering of waves in complex optical systems. However, full-wave simulations that capture multiple scattering are computationally demanding given the large system size and the ...
Ho-Chun Lin, Zeyu Wang, Chia Wei Hsu
doaj   +1 more source

Theoretical methods to treat a single dissipative bosonic mode coupled globally to an interacting many-body system

Physical Review Research, 2020
We present two approaches capable of describing the dynamics of an interacting many-body system on a lattice coupled globally to a dissipative bosonic mode.
Catalin-Mihai Halati, Ameneh Sheikhan, Corinna Kollath   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Deformable Convolutional Matrix Factorization for Document Context-Aware Recommendation in Social Networks

IEEE Access, 2019
The extreme sparsity of the rating data seriously affects the recommendation quality of the recommendation system. In order to alleviate the problem of data sparsity, some convolutional neural network (CNN)-based models make full use of text data to ...
Honglong Chen, Jinnan Fu, Lei Zhang, Shuai Wang, Kai Lin, Leyi Shi, Lianhai Wang   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Optimal Design of Sparse Matrix Phased Array Using Simulated Annealing for Volumetric Ultrasonic Imaging with Total Focusing Method

Sensors
The total focusing method (TFM) is often considered to be the ‘gold standard’ for ultrasonic imaging in the field of nondestructive testing. The use of matrix phased arrays as probes allows for high-resolution volumetric TFM imaging.
Dmitry Olegovich Dolmatov, Vadim Yurevich Zhvyrblya   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source