Results 61 to 70 of about 987,581 (290)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Modern theories of low-energy astrophysical reactions [PDF]

open access: yes, 2004
We summarize recent ab initio studies of low-energy electroweak reactions of astrophysical interest, relevant for both big bang nucleosynthesis and solar neutrino production.
Adelberger   +123 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Sparse Total Focus Imaging of Rail Transit Rail Defects Based on Grey Wolf Algorithm

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Using the ultrasonic phased array technology can realize high-precision imaging detection of rail transit rail defects. However, the widely used FMC-TFM (full matrix capture-total focusing method) has the disadvantages of long computation ...
Lubin QIAN   +4 more
doaj   +1 more source

Meso-scale analysis of ductile steel fabric/epoxy composites: numerical modelling and experimental validation [PDF]

open access: yes, 2014
This paper studies the mechanical behavior of steel fiber fabric reinforced epoxy composite on meso scale. The fabric involved is a 4-harness satin weave of innovative steel fibers with a 30 μm diameter.
Degrieck, Joris   +3 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Development and testing of a flexible image capture system based on domestic radiation-hardened electronic components

open access: yesВестник Самарского государственного технического университета. Серия: Технические науки
The aim of the work is to create a universal flexible image capture system required for recording images of various wavelength ranges in space scientific equipment.
Kirill I. Sukhachev   +3 more
doaj   +1 more source

Extending MCAS to hypernuclei and radiative-capture reactions

open access: yesEPJ Web of Conferences, 2010
Using a Multi-Channel Algebraic Scattering (MCAS) approach we have analyzed the spectra of two hypernuclear systems, 9ΛBe and 13ΛC. We have studied the splitting of the two odd-parity excited levels (1/2− and 3/2−) at 11 MeV excitation in 13ΛC ...
Svenne J.P.   +3 more
doaj   +1 more source

Comparison of Gamow-Teller strengths in the random phase approximation

open access: yes, 2013
The Gamow-Teller response is astrophysically important for a number of nuclides, particularly around iron. The random phase approximation (RPA) is an efficient way to generate strength distributions.
Johnson, Calvin W., Nabi, Jameel-Un
core   +1 more source

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