Results 11 to 20 of about 2,909 (219)

Bis(4-acetoxy-N-ethyl-N-n-propyltryptammonium) fumarate–fumaric acid (1/1)

open access: yesIUCrData, 2023
The solid-state structure of the title salt/adduct (systemic name: bis{[2-(4-acetyloxy-1H-indol-3-yl)ethyl](ethyl)propylazanium} but-2-enedioate–(E)-butenedioic acid (1/1)), 2C17H25N2O2+·C4H2O42−·C4H4O4, was determined by single-crystal X-ray diffraction.
Duyen N. K. Pham   +4 more
doaj   +1 more source

Psilacetin derivatives: fumarate salts of the methyl–ethyl, methyl–allyl and diallyl variants of the psilocin prodrug

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
The solid-state structures of the salts of three psilacetin derivatives, namely, 4-acetoxy-N-ethyl-N-methyltryptammonium (4-AcO-MET) hydrofumarate {systematic name: [2-(4-acetyloxy-1H-indol-3-yl)ethyl](methyl)ethylazanium 3-carboxyprop-2-enoate ...
Duyen N. K. Pham   +3 more
doaj   +1 more source

Bis(oxotremorine) fumarate bis(fumaric acid)

open access: yesIUCrData, 2022
The title compound, bis(oxotremorine) fumarate bis(fumaric acid) {systematic name: 1-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]pyrrolidinium (2E)-but-2-enedioate bis[(2E)-but-2-enedioic acid]}, 2C12H19N2O+·C4H2O42−·2C4H4O4, has a single oxotremorine monocation
Marilyn Naeem   +3 more
doaj   +1 more source

Synthesis of comb-like copolymers based on alkyl fumarates and their application as pour-point depressants for akshabulak crude oil

open access: yesResults in Engineering, 2023
Paraffin deposition causes numerous operational issues during the handling of waxy crude oil, and treatment with comb-structured polymeric additives can mitigate this problem.
Z. Kassenova   +4 more
doaj   +1 more source

Bioavailable central nervous system disease-modifying therapies for multiple sclerosis

open access: yesFrontiers in Immunology, 2023
Disease-modifying therapies for relapsing multiple sclerosis reduce relapse rates by suppressing peripheral immune cells but have limited efficacy in progressive forms of the disease where cells in the central nervous system play a critical role.
Hans-Peter Hartung   +8 more
doaj   +1 more source

Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes

open access: yesPharmaceuticals, 2022
Dimethyl fumarate (DMF) has emerged as a first-line therapy for relapsing-remitting multiple sclerosis (RRMS). This treatment, however, has been limited by adverse effects, which has prompted development of novel derivatives with improved tolerability ...
William R. Swindell   +2 more
doaj   +1 more source

Analyzing Discrepancies in Chemical-Shift Predictions of Solid Pyridinium Fumarates

open access: yesMolecules, 2021
Highly accurate chemical-shift predictions in molecular solids are behind the success and rapid development of NMR crystallography. However, unusually large errors of predicted hydrogen and carbon chemical shifts are sometimes reported.
Martin Dračínský
doaj   +1 more source

Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. [PDF]

open access: yes, 2019
IntroductionThe demographics of aging of the surgical population has increased the risk for perioperative neurocognitive disorders in which trauma-induced neuroinflammation plays a pivotal role.Sources of dataAfter determining the scope of the review ...
Lai, IK, Li, R, Maze, M, Saxena, S
core   +2 more sources

Unusual Formation of 1,2,4-Oxadiazine Core in Reaction of Amidoximes with Maleic or Fumaric Esters

open access: yesMolecules, 2022
We have developed a simple and convenient method for the synthesis of 3-aryl- and 3-hetaryl-1,2,4-oxadiazin-5-ones bearing an easily functionalizable (methoxycarbonyl)methyl group at position 6 via the reaction of aryl or hetaryl amidoximes with maleates
Sofia I. Presnukhina   +6 more
doaj   +1 more source

Biocompatibility and biodegradation of polyester and polyfumarate based-scaffolds for bone tissue engineering [PDF]

open access: yes, 2008
Biodegradable and biocompatible polymeric scaffolds have been recently introduced for tissue regeneration purpose. In the present study we aimed to develop polymeric-based scaffolds for bone regeneration. Two polyesters, poly-β-propiolactone (PBPL), poly-
Cortizo, Ana María   +2 more
core   +2 more sources

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