Results 31 to 40 of about 2,275 (253)

Co-crystals, Salts or Mixtures of Both? The Case of Tenofovir Alafenamide Fumarates

Pharmaceutics, 2020
Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated
Hannes Lengauer, Damjan Makuc, Damjan Šterk, Franc Perdih, Arthur Pichler, Tina Trdan Lušin, Janez Plavec, Zdenko Časar   +7 more
doaj   +1 more source

Polyphosphazenes—A Promising Candidate for Drug Delivery, Bioimaging, and Tissue Engineering: A Review

Macromolecular Materials and Engineering, 2023
Synthetic polymer materials have been surged to the forefront of research in the fields of tissue engineering, drug delivery, and biomonitoring in recent years.
Pradeep Ilayaperumal, Praveena Chelladurai, Karthik Vairan, Pooja Anilkumar, Balajothi Balagurusamy   +4 more
doaj   +1 more source

Imidazolium fumarate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
En el compuesto del título, C(3)H(5)N(2) (+)·C(4)H(3)O(4) (-), el ángulo diedro entre el anillo de imidazolio y el plano formado por el anión fumarato es 80.98 (6)°. En la estructura cristalina, los enlaces de hidrógeno O-HO y N-HO intermoleculares forman cadenas extendidas a lo largo de [100] y [01], creando una red bidimensional.
Rodolfo Moreno‐Fuquen, Javier Ellena, Jahyr E. Theodoro   +2 more
openaire   +3 more sources

Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse. [PDF]

PLoS ONE, 2010
BACKGROUND: Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis.
Darius Moharregh-Khiabani, Alexander Blank, Thomas Skripuletz, Elvira Miller, Alexandra Kotsiari, Viktoria Gudi, Martin Stangel   +6 more
doaj   +1 more source

Polymorphism and Multi-Component Crystal Formation of GABA and Gabapentin

Pharmaceutics, 2023
This study exploits the polymorphism and multi-component crystal formation of γ-amino butanoic acid (GABA) and its pharmaceutically active derivative, gabapentin.
Daniel Komisarek, Fulya Demirbas, Takin Haj Hassani Sohi, Klaus Merz, Carsten Schauerte, Vera Vasylyeva   +5 more
doaj   +1 more source

Real-world effectiveness of dimethyl fumarate versus fingolimod in a cohort of patients with multiple sclerosis using standardized, quantitative outcome metrics

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2022
Background Prior studies suggest comparable effectiveness of dimethyl fumarate (DMF) and fingolimod (FTY) in multiple sclerosis (MS) using relapse, Expanded Disability Status Scale (EDSS), and magnetic resonance imaging (MRI) lesion metrics.
Carrie M Hersh, Arman Altincatal, Nicholas Belviso, Shivani Kapadia, Carl de Moor, Richard Rudick, James Rhys Williams, Catherine Miller, Irene Koulinska   +8 more
doaj   +1 more source

COVID-19 Vaccine Response in People with Multiple Sclerosis Treated with Dimethyl Fumarate, Diroximel Fumarate, Natalizumab, Ocrelizumab, or Interferon Beta Therapy

Neurology and Therapy, 2023
Background Some multiple sclerosis (MS) disease-modifying therapies (DMTs) impair responses to vaccines, emphasizing the importance of understanding COVID-19 vaccine immune responses in people with MS (PwMS) receiving different DMTs.
Aliya Jaber, Meera Patel, Andrew Sylvester, Mary Yarussi, J. Tamar Kalina, Jason P. Mendoza, Robin L. Avila, Matthew A. Tremblay   +7 more
doaj   +1 more source

Outbreak of eczema and rhinitis in a group of office workers in Greenland [PDF]

International Journal of Circumpolar Health, 2015
Introduction: Disturbed indoor climate may in some cases be associated with illness. In the present paper, we report the results from a thorough investigation of office workers in Greenland, who developed skin and/or airway problems after moving into ...
Niels E. Ebbehøj, Tove Agner, Erik Zimerson, Magnus Bruze   +3 more
doaj   +1 more source

In vivo cortical glutathione response to oral fumarate therapy in relapsing-remitting multiple sclerosis: A single-arm open-label phase IV trial using 7-Tesla 1H MRS

NeuroImage: Clinical, 2023
Background: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy (1H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as ...
Christoph Juchem, Kelley M. Swanberg, Hetty Prinsen, Daniel Pelletier   +3 more
doaj   +1 more source

Novel drug development for neuromuscular blockade

Journal of Anaesthesiology Clinical Pharmacology, 2016
Pharmacological advances in anesthesia in recent decades have resulted in safer practice and better outcomes. These advances include improvement in anesthesia drugs with regard to efficacy and safety profiles.
Amit Prabhakar, Alan D Kaye, Melville Q Wyche, Orlando J Salinas, Kenneth Mancuso, Richard D Urman   +5 more
doaj   +1 more source