Results 31 to 40 of about 1,766 (97)

Organic-salt-mediated highly regioselective N3-alkylation of 2-thiophenytoin via Michael reaction under solvent-free conditions

Green Chemistry Letters and Reviews, 2016
A regioselective N3-alkylation of 5,5-diphenyl-2-thiohydantoin (2-thiophenytoin) using a very efficient mild base K2CO3 and α,β-unsaturated esters in the presence of organic salt TBAB (tetrabutylammonium bromide) at room temperature has been reported (3b–
Gholamhassan Imanzadeh, Aazam Aliabadi, Mohammadreza Zamanloo   +2 more
doaj   +1 more source

Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling

Acta Societatis Botanicorum Poloniae, 2017
Tree saps are nourishing biological media commonly used for beverage and syrup production. Although the nutritional aspect of tree saps is widely acknowledged, the exact relationship between the sap composition, origin, and effect on the metabolic rate ...
Artur Wnorowski, Maciej Bilek, Kinga Stawarczyk, Michał Gostkowski, Marcin Olszewski, Magdalena Wójciak-Kosior, Ireneusz Sowa   +6 more
doaj   +1 more source

Fumarate treatment in progressive forms of multiple sclerosis: first results of a single-center observational study

Therapeutic Advances in Neurological Disorders, 2014
Objectives: Therapeutic options in progressive forms of multiple sclerosis (MS) are still limited. Dimethyl fumarate (DMF) has immunomodulatory properties but may also exert antioxidative cytoprotective effects.
Katrin Strassburger-Krogias, Gisa Ellrichmann, Christos Krogias, Peter Altmeyer, Andrew Chan, Ralf Gold   +5 more
doaj   +1 more source

Lymphocyte dynamics in patients with multiple sclerosis who were treated with dimethyl fumarate and subsequently switched to diroximel fumarate

Brain Disorders
Objective: Dimethyl fumarate (DMF) and diroximel fumarate (DRF) are oral multiple sclerosis (MS) disease-modifying therapies (DMTs). Absolute lymphocyte count (ALC) dynamics are similar for DMF and DRF, but have not been investigated in patients who ...
Shauna M. Gales, Ahmed Z. Obeidat, Andreina Neall, Kermit A. Lloyd, Nicholas Belviso, Seth Levin, Ivan Bozin, Jason P. Mendoza, James B. Lewin, Michael D. Kornberg   +9 more
doaj   +1 more source

Evolving Patterns of Initial RRMS Treatment in Finland (2013–2022): Insights From a Nationwide Multiple Sclerosis Register

Brain and Behavior
Background The treatment of relapsing‐remitting multiple sclerosis (RRMS) is changing. There are limited data about initial treatment of RRMS in Finland. Objective Our objectives were to study the trends of initial disease‐modifying treatments (DMTs) for
Henrik Ahvenjärvi, Elina Jokinen, Matias Viitala, Henri Autio, Anne M. Portaankorva, Merja Soilu‐Hänninen, Johanna Krüger, Mervi Ryytty   +7 more
doaj   +1 more source

Autoimmune skin diseases in multiple sclerosis

Neurology Perspectives
Introduction: Autoimmune dermatological diseases have a prevalence greater than 2% in the general population, sometimes as a primary disorder and other times within a context of systemic involvement.
M. Roncero Riesco, A. Cabanillas Cabral, Y. El Berdei Montero   +2 more
doaj   +1 more source

Fumaric acid esters in the management of psoriasis

Psoriasis: Targets and Therapy, 2015
Deepak MW Balak Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands Abstract: Fumaric acid esters (FAE) are small molecules with immunomodulating, anti-inflammatory, and anti-oxidative effects. FAE were introduced as a systemic
Balak DMW
doaj  

Shifting from the treat-to-target to the early highly effective treatment approach in patients with multiple sclerosis – real-world evidence from Germany

Therapeutic Advances in Neurological Disorders
Background: While evidence highlights the effectiveness of initiating disease-modifying therapy with a high-efficacy medication for multiple sclerosis (MS) patients with poor prognostic factors, it remains unclear whether this approach has been adopted ...
Steffeni Papukchieva, Ann-Sophie Stratil, Maria Kahn, Nils-Henning Neß, Maike Hollnagel-Schmitz, Vivien Gerencser, Julia Rustemeier, Markus Eberl, Benjamin Friedrich, Tjalf Ziemssen   +9 more
doaj   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment-Real-World Historical Cohort Study. [PDF]

Clin Pharmacol Ther
Rosh B, Levi O, Stein N, Yahav A, Gronich N.   +4 more
europepmc   +1 more source

Maleic Anhydride and Its Derivatives: A Brief Review of Reactivity and Properties in Radical (Co)Polymerizations. [PDF]

Macromol Rapid Commun
Smith MP, Klumperman B.
europepmc   +1 more source