Results 11 to 20 of about 1,766 (97)

Psilacetin derivatives: fumarate salts of the methyl–ethyl, methyl–allyl and diallyl variants of the psilocin prodrug

Acta Crystallographica Section E: Crystallographic Communications, 2021
The solid-state structures of the salts of three psilacetin derivatives, namely, 4-acetoxy-N-ethyl-N-methyltryptammonium (4-AcO-MET) hydrofumarate {systematic name: [2-(4-acetyloxy-1H-indol-3-yl)ethyl](methyl)ethylazanium 3-carboxyprop-2-enoate ...
Duyen N. K. Pham, Andrew R. Chadeayne, James A. Golen, David R. Manke   +3 more
doaj   +1 more source

Bis(4-acetoxy-N-ethyl-N-n-propyltryptammonium) fumarate–fumaric acid (1/1)

IUCrData, 2023
The solid-state structure of the title salt/adduct (systemic name: bis{[2-(4-acetyloxy-1H-indol-3-yl)ethyl](ethyl)propylazanium} but-2-enedioate–(E)-butenedioic acid (1/1)), 2C17H25N2O2+·C4H2O42−·C4H4O4, was determined by single-crystal X-ray diffraction.
Duyen N. K. Pham, Nathan B. Sackett, Andrew R. Chadeayne, James A. Golen, David R. Manke   +4 more
doaj   +1 more source

Bis(oxotremorine) fumarate bis(fumaric acid)

IUCrData, 2022
The title compound, bis(oxotremorine) fumarate bis(fumaric acid) {systematic name: 1-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]pyrrolidinium (2E)-but-2-enedioate bis[(2E)-but-2-enedioic acid]}, 2C12H19N2O+·C4H2O42−·2C4H4O4, has a single oxotremorine monocation
Marilyn Naeem, Andrew R. Chadeayne, James A. Golen, David R. Manke   +3 more
doaj   +1 more source

Synthesis of comb-like copolymers based on alkyl fumarates and their application as pour-point depressants for akshabulak crude oil

Results in Engineering, 2023
Paraffin deposition causes numerous operational issues during the handling of waxy crude oil, and treatment with comb-structured polymeric additives can mitigate this problem.
Z. Kassenova, S. Kozhabekov, A. Zhubanov, A. Galymzhan, T. Seilkhanov   +4 more
doaj   +1 more source

Bioavailable central nervous system disease-modifying therapies for multiple sclerosis

Frontiers in Immunology, 2023
Disease-modifying therapies for relapsing multiple sclerosis reduce relapse rates by suppressing peripheral immune cells but have limited efficacy in progressive forms of the disease where cells in the central nervous system play a critical role.
Hans-Peter Hartung, Hans-Peter Hartung, Hans-Peter Hartung, Hans-Peter Hartung, Bruce A.C. Cree, Michael Barnett, Sven G. Meuth, Amit Bar-Or, Lawrence Steinman   +8 more
doaj   +1 more source

Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes

Pharmaceuticals, 2022
Dimethyl fumarate (DMF) has emerged as a first-line therapy for relapsing-remitting multiple sclerosis (RRMS). This treatment, however, has been limited by adverse effects, which has prompted development of novel derivatives with improved tolerability ...
William R. Swindell, Krzysztof Bojanowski, Ratan K. Chaudhuri   +2 more
doaj   +1 more source

Analyzing Discrepancies in Chemical-Shift Predictions of Solid Pyridinium Fumarates

Molecules, 2021
Highly accurate chemical-shift predictions in molecular solids are behind the success and rapid development of NMR crystallography. However, unusually large errors of predicted hydrogen and carbon chemical shifts are sometimes reported.
Martin Dračínský
doaj   +1 more source

Sleep-related breathing disorder (central sleep apnoea) improved coincidentally by medical therapy with fumarates (dimethyl fumarate)

Drugs in Context, 2023
Central sleep apnoea (CSA) is a sleep disorder characterized by the repeated cessation or reduction of both airflow and ventilatory effort when sleeping.
Abdulmajeed M Albadi, Mana M Alshahrani, Riyad O Allehebi   +2 more
doaj   +1 more source

Unusual Formation of 1,2,4-Oxadiazine Core in Reaction of Amidoximes with Maleic or Fumaric Esters

Molecules, 2022
We have developed a simple and convenient method for the synthesis of 3-aryl- and 3-hetaryl-1,2,4-oxadiazin-5-ones bearing an easily functionalizable (methoxycarbonyl)methyl group at position 6 via the reaction of aryl or hetaryl amidoximes with maleates
Sofia I. Presnukhina, Marina V. Tarasenko, Kirill K. Geyl, Svetlana O. Baykova, Sergey V. Baykov, Anton A. Shetnev, Vadim P. Boyarskiy   +6 more
doaj   +1 more source

Tetrabutylammonium Bromide Media Aza-Michael Addition of 1,2,3,6-Tetrahydrophthalimide to Symmetrical Fumaric Esters and Acrylic Esters under Solvent-Free Conditions

Molecules, 2010
The aza-Michael addition of 1,2,3,6-tetrahydrophthalimide with symmetrical fumaric esters has been performed efficiently in a solvent-free system at 100 °C and using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a base in the presence of tetrabutylammonium ...
Mohammadreza Zamanloo, Yagoub Mansoori, Gholamhassan Imanzadeh, Farzaneh Ahmadi   +3 more
doaj   +1 more source