Results 21 to 30 of about 12,559 (263)
Molecules, 2010 The aza-Michael addition of 1,2,3,6-tetrahydrophthalimide with symmetrical fumaric esters has been performed efficiently in a solvent-free system at 100 °C and using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a base in the presence of tetrabutylammonium ...
Mohammadreza Zamanloo +3 more
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Acta Crystallographica Section E Structure Reports Online, 2009 En el compuesto del título, C(3)H(5)N(2) (+)·C(4)H(3)O(4) (-), el ángulo diedro entre el anillo de imidazolio y el plano formado por el anión fumarato es 80.98 (6)°. En la estructura cristalina, los enlaces de hidrógeno O-HO y N-HO intermoleculares forman cadenas extendidas a lo largo de [100] y [01], creando una red bidimensional.
Rodolfo Moreno‐Fuquen +2 more
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Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery
Pharmaceutics, 2022 Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is administered as a fumarate salt for the treatment of acid-related diseases, including reflux esophagitis,
Min-Jeong Lee +6 more
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Co-crystals, Salts or Mixtures of Both? The Case of Tenofovir Alafenamide Fumarates
Pharmaceutics, 2020 Tenofovir alafenamide fumarate (TAF) is the newest prodrug of tenofovir that constitutes several drug products used for the treatment of HIV/AIDS. Although the solid-state properties of its predecessor tenofovir disoproxil fumarate have been investigated
Hannes Lengauer +7 more
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Macromolecular Materials and Engineering, 2023 Synthetic polymer materials have been surged to the forefront of research in the fields of tissue engineering, drug delivery, and biomonitoring in recent years.
Pradeep Ilayaperumal +4 more
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Effects of fumaric acids on cuprizone induced central nervous system de- and remyelination in the mouse. [PDF]
PLoS ONE, 2010 BACKGROUND: Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis.
Darius Moharregh-Khiabani +6 more
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Aminoguanidinium hydrogen fumarate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 The title compound, CH(7)N(4) (+)·C(4)H(3)O(4) (-), is a molecular salt in which the amino-guanidinium cations and fumarate monoanions are close to planar, with maximum deviations of 0.011 (1) and 0.177 (1) Å, respectively. The crystal packing is stabilized by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds.
Murugavel, Swaminathan +4 more
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Neurology and Therapy, 2023 Background Some multiple sclerosis (MS) disease-modifying therapies (DMTs) impair responses to vaccines, emphasizing the importance of understanding COVID-19 vaccine immune responses in people with MS (PwMS) receiving different DMTs.
Aliya Jaber +7 more
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NeuroImage: Clinical, 2023 Background: This is an open-label, single-arm, single-center pilot study using 7-Tesla in vivo proton magnetic resonance spectroscopy (1H MRS) to measure brain cortical glutathione concentration at baseline before and during the use of oral fumarates as ...
Christoph Juchem +3 more
doaj +1 more source
Outbreak of eczema and rhinitis in a group of office workers in Greenland [PDF]
International Journal of Circumpolar Health, 2015 Introduction: Disturbed indoor climate may in some cases be associated with illness. In the present paper, we report the results from a thorough investigation of office workers in Greenland, who developed skin and/or airway problems after moving into ...
Niels E. Ebbehøj +3 more
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