The Fumarprotocetraric Acid Inhibits Tau Covalently, Avoiding Cytotoxicity of Aggregates in Cells [PDF]
Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory response.
Camila González +5 more
doaj +6 more sources
Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro [PDF]
IntroductionRespiratory syncytial virus (RSV) remains a major international public health concern. However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care.
Chao Wang +15 more
doaj +3 more sources
Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen Cladonia metacorallifera [PDF]
Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification ...
Beatriz Sepúlveda +4 more
doaj +2 more sources
The Genus Cetraria s. str.—A Review of Its Botany, Phytochemistry, Traditional Uses and Pharmacology [PDF]
The genus Cetraria s. str. (Parmeliaceae family, Cetrarioid clade) consists of 15 species of mostly erect brown or greenish yellow fruticose or subfoliose thallus.
Marta Sánchez +4 more
doaj +2 more sources
Lichens are widely distributed around the world. Their phenolic compounds, consisting mainly of depsides and depsidones, have been extensively studied for important biological activities.
Luiz Fabrício Gardini Brandão +6 more
doaj +4 more sources
Cyclodextrin-Based Systems of Cetraria islandica Extracts: A Novel Approach to Improve Solubility and Biological Activity of Lichen-Derived Natural Products [PDF]
Cetraria islandica (L.) Ach. (CI) is a lichen from the Parmeliaceaea family used in medicine. However, the low solubility of CI secondary metabolites in water limits the application of lichen extract and compounds.
Elżbieta Studzińska-Sroka +5 more
doaj +2 more sources
The phylogeny and taxonomy of Violella (Tephromelataceae, lichenized Ascomycota), including a new species from China [PDF]
Violella yunnanensis C. J. Zhong & L. Hu is described as new to science. It is characterized by its esorediate, areolate to weakly warted thallus, hymenium heavily pigmented with Fucatus-violet pigment, brownish inner ascospore walls, and its ...
Chun-jiao Zhong, Zun-tian Zhao, Ling Hu
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Optimizing the Extraction of Polyphenols from Different Edible Lichens Using Response Surface Methodology and the Determination of Their Mineral and Antibacterial Properties [PDF]
This study employed response surface methodology for the first-time optimization of the ultrasound-assisted extraction (UAE) of the total phenolic content (TPC) and ABTS from edible lichens, including Evernia divaricata, Evernia prunastri, Pseudevernia ...
Kubra Ozkan +8 more
doaj +2 more sources
The allelopathic activity of the different extracts of the lichen Cladonia verticillaris and fumarprotocetraric acid on the early growth of A cepa (IPA 6) seedlings depends on their chemical composition and concentration, respectively.
A. M. Yano-Melo +2 more
doaj +3 more sources
Diversity of secondary lichen metabolites was studied in epiphytic lichens on six phorophytes—spruce, pine, birch, alder, aspen and poplar in the Middle Urals of Russia. Atranorin, usnic, fumarprotocetraric acid, zeorin, and gyrophoric acid were found in
Alexander Paukov +4 more
doaj +1 more source

