Results 111 to 120 of about 3,137 (203)

The inducers 1,3-diaminopropane and spermidine cause the reprogramming of metabolism in Penicillium chrysogenum, leading to multiple vesicles and penicillin overproduction [PDF]

, 2013
In this article we studied the differential protein abundance of Penicillium chrysogenum in response to either 1,3-diaminopropane (1,3-DAP) or spermidine, which behave as inducers of the penicillin production process.
Barreiro, Carlos., García-Estrada, Carlos., Jami, Mohammad-Saeid., Martín, Juan-Francisco., Martín-González, Jorge.   +4 more
core  

Mitochondrial enzyme FAHD1 reduces ROS in osteosarcoma

Scientific Reports
This study investigated the impact of overexpressing the mitochondrial enzyme Fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) in human osteosarcoma epithelial cells (U2OS) in vitro.
Anne Heberle, Elia Cappuccio, Andreas Andric, Tatjana Kuen, Anna Simonini, Alexander K. H. Weiss   +5 more
doaj   +1 more source

Progress in Gene Therapy for Hereditary Tyrosinemia Type 1

Pharmaceutics
Hereditary Tyrosinemia Type-1 (HT1), an inherited error of metabolism caused by a mutation in the fumarylacetoacetate hydrolase gene, is associated with liver disease, severe morbidity, and early mortality.
Helen Thomas, Robert C. Carlisle
doaj   +1 more source

A Lithuanian Case of Tyrosinemia Type 1 with a Literature Review: A Rare Cause of Acute Liver Failure in Childhood

Medicina
Hereditary type 1 tyrosinemia (HT1) is a rare inherited autosomal recessive disorder of tyrosine metabolism, characterized by progressive liver damage, dysfunction of kidney tubules, and neurological crises.
Rūta Rokaitė, Agnė Čibirkaitė, Vykinta Zeleckytė, Gabija Lazdinytė, Mindaugas Dženkaitis   +4 more
doaj   +1 more source

The Tyrosinemia Type I [PDF]

, 2013
Tyrosinemia type 1 is an autosomal recessive disorder which can be detected as early as possible after birth so that it may be treated or alleviated immediately. If untreated, the disorder can cause dysfunctions of liver, kidney, or neurological disease.
Nelwan, Martin L.
core   +1 more source

CHARACTERIZATION OF FUMARYLACETOACETATE FUMARYL HYDROLASE.

, 1976
Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1976 .M239. Source: Dissertation Abstracts International, Volume: 37-06, Section: B, page: 2829. Thesis (Ph.D.)--University of Windsor (Canada), 1976.
openaire   +2 more sources

Altered myelination as a proposed mechanism for neurocognitive dysfunction observed in mice with Tyrosinemia type 1 [PDF]

, 2018
The exact mechanism behind the recent reports of impaired neurocognitive function in individuals with the rare genetic disorder Hereditary Tyrosinemia Type I (HT1) has yet to be determined.
Moore, Marissa E.
core   +1 more source

Intrahepatic Exhausted Antiviral Immunity in an Immunocompetent Mouse Model of Chronic Hepatitis BSummary

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Targeting exhausted immune systems would be a promising therapeutic strategy to achieve a functional cure for HBV infection in patients with chronic hepatitis B (CHB). However, animal models recapitulating the immunokinetics of CHB
Satoshi Shigeno, Takahiro Kodama, Kazuhiro Murai, Daisuke Motooka, Akihisa Fukushima, Akira Nishio, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Tatsuya Kanto, Tetsuo Takehara   +10 more
doaj   +1 more source

Taql RFLP for the human fumarylacetoacetate hydrolase (FAH) gene

Nucleic Acids Research, 1991
S I, Demers, D, Phaneuf, R M, Tanguay
openaire   +3 more sources

Bringing up to date the toolkit for the catabolism of aromatic compounds in fungi: The unexpected 1,2,3,5‐tetrahydroxybenzene central pathway

Microbial Biotechnology
Saprophytic fungi are able to catabolize many plant‐derived aromatics, including, for example, gallate. The catabolism of gallate in fungi is assumed to depend on the five main central pathways, i.e., of the central intermediates' catechol ...
Tiago M. Martins, Artur Bento, Celso Martins, Ana S. Tomé, Carlos J. S. Moreira, Cristina Silva Pereira   +5 more
doaj   +1 more source