Results 81 to 90 of about 302,091 (291)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Approximation to Conjugate Functions [PDF]

open access: yesProceedings of the American Mathematical Society, 1951
The object of the present note is the establishment of the following theorem: THEOREM 1. If { Tn(x) } is a sequence of trigonometric polynomials of order n, and if (1) f(x) T.(x) = O(n-"a) (a > 0) uniformly in x, then the conjugate function and the conjugate trigonometric polynomials satisfy (2) f(x) T(x) = O(n-a log n) uniformly in x.
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Approximation for the gamma function via the tri-gamma function

open access: yesJournal of Inequalities and Applications, 2017
In this paper, we present a new sharp approximation for the gamma function via the tri-gamma function. This approximation is fast in comparison with the recently discovered asymptotic series.
Xu You, Xiaocui Li
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

A Neural Network Approximation Based on a Parametric Sigmoidal Function

open access: yesMathematics, 2019
It is well known that feed-forward neural networks can be used for approximation to functions based on an appropriate activation function. In this paper, employing a new sigmoidal function with a parameter for an activation function, we consider a ...
Beong In Yun
doaj   +1 more source

Continuous approximation of quasiplurisubharmonic functions [PDF]

open access: green, 2015
Philippe Eyssidieux   +2 more
openalex   +1 more source

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