Results 101 to 110 of about 14,444,288 (391)
Plant functional biology [PDF]
American Journal of Botany, 2004 David Ackerly and Russ Monson took on a daunting task in organizing the symposium that led to this collection of papers: identifying a representative set of studies of plant function that together might point the way to a coherent field of evolutionary inquiry into plant functional biology.
openaire +2 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
A Distribution Function Arising in Computational Biology
, 2000 Karlin and Altschul in their statistical analysis for multiple high-scoring segments in molecular sequences introduced a distribution function which gives the probability there are at least r distinct and consistently ordered segment pairs all with score
Tracy, Craig A., Widom, Harold
core +1 more source
A homozygous genome‐edited Sept2‐EGFP fibroblast cell line [PDF]
, 2019 Septins are a conserved, essential family of GTPases that interact with actin, microtubules, and membranes and form scaffolds and diffusion barriers in cells. Several of the 13 known mammalian septins assemble into nonpolar, multimeric complexes that can
Banko, Monika +4 more
core +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution
Molecular biology and evolution, 2018 DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and ...
X. Xia
semanticscholar +1 more source
Interaction of the pioneer transcription factor GATA3 with nucleosomes
Nature Communications, 2020 GATA 3 functions as a pioneer factor during cellular reprogramming. Here the authors delineate nucleosome positioning relative to GATA3 binding motifs and describe the structure of a GATA3–nucleosome complex; providing insight into how a pioneer factor ...
Hiroki Tanaka +7 more
doaj +1 more source
Boolean nested canalizing functions: a comprehensive analysis
, 2013 Boolean network models of molecular regulatory networks have been used successfully in computational systems biology. The Boolean functions that appear in published models tend to have special properties, in particular the property of being nested ...
Adeyeye, John O. +4 more
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Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence. [PDF]
, 2020 There is a growing body of literature demonstrating the importance of T cell exhaustion in regulating and shaping immune responses to pathogens and cancer.
Canter, Robert J +2 more
core
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source