Results 51 to 60 of about 14,894,566 (393)

BRL1 and BRL3 are novel brassinosteroid receptors that function in vascular differentiation in Arabidopsis [PDF]

open access: yes, 2004
Plant steroid hormones, brassinosteroids (BRs), are perceived by the plasma membrane-localized leucine-rich-repeat-receptor kinase BRI1. Based on sequence similarity, we have identified three members of the BRI1 family, named BRL1, BRL2 and BRL3.
Caño Delgado, Ana   +8 more
core   +1 more source

Photoactive siderophores: Structure, function and biology

open access: yesJournal of Inorganic Biochemistry, 2021
It is well known that bacteria and fungi have evolved sophisticated systems for acquiring the abundant but biologically inaccessible trace element iron. These systems are based on high affinity Fe(III)-specific binding compounds called siderophores which function to acquire, transport, and process this essential metal ion. Many hundreds of siderophores
Alison, Butler   +3 more
openaire   +2 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

The structural basis of translational control by eIF2 phosphorylation

open access: yesNature Communications, 2019
During the integrated stress response, translation is modulated through the phosphorylation of translation initiation factor eIF2 and the formation of a complex with eIF2B.
Tomas Adomavicius   +6 more
doaj   +1 more source

'Causa efficiens' versus 'Causa finalis': functional explanations in biology [PDF]

open access: yes, 2011
Biology differs from most sciences in its particular way of dealing with the term ‘function’. On the one hand, questions like ‘What is the function of a trait x?’ seem to be perfectly legitimate, realizing that (most) biologists acknowledge that ...
Kosolosky, Laszlo
core   +1 more source

Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design [PDF]

open access: yes, 2009
The main task of the medicinal chemist is to design molecules that interact specifically with derailed or degenerating processes in a diseased organism, translating the available knowledge of pathobiochemical and physiological data into chemically ...
Bruijnincx, Pieter C. A., Sadler, P. J.
core   +1 more source

Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Learning biological properties from sequence data is a logical step toward generative and predictive artificial intelligence for biology.
Alexander Rives   +7 more
semanticscholar   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small   +3 more
wiley   +1 more source

Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis

open access: yesScientific Reports, 2021
The Sec61 complex translocates nascent polypeptides into and across the membrane of the endoplasmic reticulum (ER), providing access to the secretory pathway. In this study, we show that Ipomoeassin-F (Ipom-F), a selective inhibitor of protein entry into
Peristera Roboti   +4 more
doaj   +1 more source

Herbal Extract Mixture Modulates Intestinal Antioxidative Capacity and Microbiota in Weaning Piglets

open access: yesFrontiers in Microbiology, 2021
Recently, herbal extracts have been applied in multiple aspects, such as medicine and animal feed. Different compositions of herbal extract mixture (HEM) have various components and diverse functions.
Meiwei Wang   +7 more
doaj   +1 more source

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