Results 61 to 70 of about 3,596,843 (342)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Nature CommunicationsDespite the importance of keratinocytes in epidermal structure and function, the molecular mechanisms regulating the division of these cells remain poorly understood. Herein, we demonstrate an essential role for cilia and flagella associated protein 100 (
Shuang Sun +9 more
doaj +1 more source
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis
Scientific Reports, 2017 Myeloid cells, key players in atherosclerosis, take up and present antigens, leading to systemic and local T cell activation. The recruitment and activation of immune cells to the aorta in atherosclerosis is regulated by adhesion molecules, chemokines ...
Iuliia O. Peshkova +4 more
doaj +1 more source
Understanding Genomic Evolution of Olfactory Receptors through Fractal and Mathematical Morphology [PDF]
, 2011 Fractals and Mathematical Morphology are immensely used to study many problems in different branches of science and technology including the domain of Biology. There are many more unrevealed facts and figures of genes and genome in Computational Biology.
Arunava Goswami +5 more
core +1 more source
An evolutionary approach to Function [PDF]
, 2009 The distinction between function and role is a vexed and difficult one. While the distinction appears to be useful, in practice it is hard to apply; this can be even worse when applying this distinction to biology.
Phillip Lord
core +4 more sources
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit
Nature Communications, 2023 Bacteria swim using a flagellar motor that is powered by stator units. Vibrio spp. are highly motile bacteria responsible for various human diseases, the polar flagella of which are exclusively driven by sodium-dependent stator units (PomAB).
Haidai Hu +10 more
doaj +1 more source
Chiral separation in microflows [PDF]
, 2005 Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology and belongs ...
A. J. Lichtenberg +8 more
core +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Primate Craniofacial Function and Biology [PDF]
, 2010 Book review: Primate Craniofacial Function and ...
Constantino, Paul J
core +1 more source