Results 61 to 70 of about 14,637,911 (412)
Population Ecology, EarlyView.In this article, we tested optimal SNP filtering strategies for accurate parentage assignment and pedigree reconstruction for a wild population of red‐spotted masu salmon, Oncorhynchus masou ishikawae. We found that mid‐point filtering in terms of call rate and minor allele frequency performs well for pedigree reconstruction.
Shohei Noda +6 more
wiley +1 more source
GTP binding to translation factor eIF2B stimulates its guanine nucleotide exchange activity
iScience, 2021 Summary: eIF2B is the guanine nucleotide exchange factor (GEF) required for cytoplasmic protein synthesis initiation in eukaryotes and its regulation within the integrated stress response (ISR).
Christopher J. Kershaw +5 more
doaj
Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit
Nature Communications, 2023 Bacteria swim using a flagellar motor that is powered by stator units. Vibrio spp. are highly motile bacteria responsible for various human diseases, the polar flagella of which are exclusively driven by sodium-dependent stator units (PomAB).
Haidai Hu +10 more
doaj +1 more source
Building Block and Building Rule: Dual Descriptor Method for Biological Sequence Analysis [PDF]
, 2008 The emergence of “Systems Biology” in recent years highlights the systematic viewpoint of bio-system modeling. Building on such a background, Dual Descriptor Method, a generic methodology for biological sequence analysis is proposed. From a
Bin-Guang Ma
core +1 more source
Nuclear protein phosphatases with Kelch-repeat domains modulate the response to brassinosteroids in Arabidopsis [PDF]
, 2004 Perception of the plant steroid hormone brassinolide (BL) by the membrane-associated receptor kinase BRI1 triggers the dephosphorylation and accumulation in the nucleus of the transcriptional modulators BES1 and BZR1.
Caño Delgado, Ana +5 more
core +2 more sources
Evaluating the origin and spread of spotted lanternfly (Lycorma delicatula) in Japan
Population Ecology, EarlyView.The invasive spotted lanternfly (Lycorma delicatula) is native to China and is a serious economic pest in the Republic of Korea and the United States, though it is not considered a pest in Japan. We established a distribution map of L. delicatula in Japan through a comprehensive review of published literature and citizen science reports and analyzed ...
Matthew T. Kamiyama +5 more
wiley +1 more source
IL-27R signaling controls myeloid cells accumulation and antigen-presentation in atherosclerosis
Scientific Reports, 2017 Myeloid cells, key players in atherosclerosis, take up and present antigens, leading to systemic and local T cell activation. The recruitment and activation of immune cells to the aorta in atherosclerosis is regulated by adhesion molecules, chemokines ...
Iuliia O. Peshkova +4 more
doaj +1 more source
Patterns of Differentially Expressed circRNAs in Human Thymocytes
Non-Coding RNA, 2022 Circular RNAs (circRNAs) are suggested to play a discriminative role between some stages of thymocyte differentiation. However, differential aspects of the stage of mature single-positive thymocytes remain to be explored.
Pilar López-Nieva +7 more
doaj +1 more source
The Impact of Genomic Variation on Function (IGVF) Consortium [PDF]
arXiv, 2023 Our genomes influence nearly every aspect of human biology from molecular and cellular functions to phenotypes in health and disease. Human genetics studies have now associated hundreds of thousands of differences in our DNA sequence ("genomic variation") with disease risk and other phenotypes, many of which could reveal novel mechanisms of human ...
arxiv
De novo design of bioactive protein switches. [PDF]
, 2019 Allosteric regulation of protein function is widespread in biology, but is challenging for de novo protein design as it requires the explicit design of multiple states with comparable free energies. Here we explore the possibility of designing switchable
Baker, David +14 more
core