Results 101 to 110 of about 1,366,798 (265)
Communications BiologyDuring the wound healing process, the activation of signal transducer and activator of transcription 3 (STAT3) is considered crucial for the migration and proliferation of epithelial cells, as well as for establishing the inflammatory environment ...
Fangqing Deng +10 more
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The meaning and change in the function of communal space in Lamin house
ARTEKS : Jurnal Teknik ArsitekturIn the modern era, many traditional houses have changed to functional spaces, as stated in several journals, including the Lamin house in East Kalimantan.
Abdul Mufti Radja +3 more
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
In die Skriflig, 2014 Daniel 1 narrates how Daniel and his friends come from Jerusalem and are appointed as officials at the royal court in Babylon. The narrative is governed by the various and significant references to space.
Marius Nel
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Journal of the London Mathematical Society, 2000 We classify simple singularities of functions on space curves. We show that their bifurcation sets have properties very similar to those of functions on smooth manifolds and complete intersections [1,2]: the k(pi, 1)-theorem for the bifurcations diagram of functions is true, and both this diagram and the discriminant are Saito's free divisors.
openaire +2 more sources
The Approximation Characteristics of Weighted Band-Limited Function Space
MathematicsThis article primarily investigates the width problem within weighted band-limited function space in a uniform setting. Through an analysis of the properties of s-numbers, we establish a connection between the widths of weighted band-limited function ...
Yue Li +3 more
doaj +1 more source