Results 101 to 110 of about 10,585,569 (293)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Phosphine Depletion in Brown Dwarf Atmospheres Explained due to Metal Phosphide Formation

open access: yesThe Astrophysical Journal Letters
Phosphine (PH _3 ) is predicted to be the dominant phosphorus-bearing gas in cool substellar atmospheres, yet observations have revealed a puzzling pattern.
Rongzhang Yin   +3 more
doaj   +1 more source

Micro-CT-Based Pore Network Characterization and Microscopic Permeability Prediction Modeling for Deep Low-Rank Coal in the Tiefa Basin

open access: yesFractal and Fractional
Deep low-rank coal from the Daqiang Mine in the Tiefa Basin was investigated using micro-CT imaging with a voxel size of 1 μm. The CT-resolved connected macropore structures of 12 representative elementary volumes (REVs) were reconstructed, and ...
Shuaidong Wang   +4 more
doaj   +1 more source

Chaotic Attractor Generation via Space Function Controls

open access: yesDiscrete Dynamics in Nature and Society, 2011
The analysis of chaotic attractor generation is given, and the generation of novel chaotic attractor is introduced in this paper. The underlying mechanism involves two simple linear systems with one-dimensional, two-dimensional, or three-dimensional ...
Hong Shi, Guangming Xie, Desheng Liu
doaj   +1 more source

On a Space of Besicovitch Functions

open access: yesReal Analysis Exchange, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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