Results 111 to 120 of about 1,559,492 (313)

Reflections on function spaces

open access: yesAnnals of Pure and Applied Logic, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Organising family life: An analysis of the spatial organisation of people and activities in the household [PDF]

open access: yes, 2019
How Cultural Patterns Are Reflected On Domestic Space Has Been Vastly Discussed In Space Syntax Literature. The Genotype Analogy Was Developed With The Underlying Notion That The Configurational Properties Of Architectural Function Reflect Patterns Of
Varoudis, T   +3 more
core  

Approximating Continuous Function by Smooth Functions on Orbit Spaces

open access: yesMathematics
In this paper, we study the approximation of continuous functions on a subclass of singular space—the subcartesian space. As is well known, the orbit space of the proper action of a Lie group on a smooth manifold is a subcartesian space.
Luyang Zhou, Qianqian Xia
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Perception and Function in Occupant-Space Relationship [PDF]

open access: yes, 2012
How can architects improve the relationship between the occupant and the space in regards to offering the occupant and enjoyable experience, which also fulfills their needs and expectations of function?
Bayramzadeh, Sara
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Adjoining a Constant Function to n-Dimensional Chebyshev Space

open access: yesJournal of Function Spaces, 2016
This paper is concerned with extending a Chebyshev system of n continuous nonconstant functions into a set of n+1 functions including a constant function. Necessary and sufficient conditions for the new set to be a Chebyshev system are discussed and some
Mansour Alyazidi-Asiry
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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