Results 131 to 140 of about 10,585,569 (293)

Clustering dichotomously scored items through functional k-means algorithm

open access: yes, 2016
In the educational field, it is common to analyze the probability of a correct response to a test item as a continuous function of the item parameters and the subject ability. This relation is given by the item response function.
Di Battista, Tonio; Dipartimento di Metodi Quantitativi e Teoria Economica, Università "G. d'Annunzio" Chieti-Pescara   +3 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Function of space in Daniel 1

open access: yesIn die Skriflig, 2014
Daniel 1 narrates how Daniel and his friends come from Jerusalem and are appointed as officials at the royal court in Babylon. The narrative is governed by the various and significant references to space.
Marius Nel
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Agile in Orbit: Enabling Our Mission Partners to Thrive in the Ever-Changing Space Domain

open access: yes
At SDL, agility is a quality of both our mission approach and our space ...
Space Dynamics Laboratory
core   +1 more source

Topologies for function spaces [PDF]

open access: yesPacific Journal of Mathematics, 1951
Arens, Richard, Dugundji, James
openaire   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Organising family life: An analysis of the spatial organisation of people and activities in the household [PDF]

open access: yes, 2019
How Cultural Patterns Are Reflected On Domestic Space Has Been Vastly Discussed In Space Syntax Literature. The Genotype Analogy Was Developed With The Underlying Notion That The Configurational Properties Of Architectural Function Reflect Patterns Of
Varoudis, T   +3 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy