Results 121 to 130 of about 1,559,492 (313)
Anaerobic oxidation of methane by manganese oxides in marine sediments: a review
Frontiers in Marine ScienceAnaerobic oxidation of methane (AOM) is a key methane sink in marine sediments, driven by electron acceptors such as sulfate, nitrate, and metal oxides. Manganese (Mn) oxides, owing to their high oxidizing capacity and rapid turnover, are also recognized
Yuan Xue +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
On a Space of Besicovitch Functions
Real Analysis Exchange, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
“The Function of Urban Space in "In the Skin of a Lion" by Michael Ondaatje”
, 2017 The slogan of Tourism Toronto today “The World in One City” explicitly signifies the city’s multinational nature, its new identity as a “polyphonous city of many cultures” (Rosenthal 2011, p.32).
Pirhulyieva, Jakhan
core
Communications BiologyDuring the wound healing process, the activation of signal transducer and activator of transcription 3 (STAT3) is considered crucial for the migration and proliferation of epithelial cells, as well as for establishing the inflammatory environment ...
Fangqing Deng +10 more
doaj +1 more source
The meaning and change in the function of communal space in Lamin house
ARTEKS : Jurnal Teknik ArsitekturIn the modern era, many traditional houses have changed to functional spaces, as stated in several journals, including the Lamin house in East Kalimantan.
Abdul Mufti Radja +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source