Results 111 to 120 of about 832,157 (268)
Thrombosis JournalBackground and objective Left ventricular thrombus (LVT) formation in patients with acute myocardial infarction (AMI) or cardiomyopathies is not uncommon. The optimal oral anticoagulation therapy for resolving LVT has been under intense debate. Vitamin K
Tong Hu +5 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Scientific ReportsTirofiban is a glycoprotein IIb/IIIa receptor blocker mainly used alongside other blood thinners in patients with acute coronary syndrome (ACS) undergoing procedures like angioplasty (PCI).
Qian Guo +8 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Osgood’s theory of functions [PDF]
Bulletin of the American Mathematical Society, 1907 openaire +2 more sources
(Yeni) Bir Sözlükbilim Teorisine İhtiyacımız Var mı? Sven Tarp
Dil ve Edebiyat Araştırmaları Dergisi, 2014 Hâlihazırdaki basılı sözlüklerden elektronik sözlüklere geçiş evresinde, sözlükbilimsel elektronik araçların anlayış ve üretimine rehberlik edebilecek yeni bir sözlükbilim teorisine ihtiyaç duyup duymadığımız ya da zaten basılmış eserler döneminde ...
Çeviren: Fatih Doğru
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Perbedaan Model dan Teori dalam Ilmu Komunikasi
Humaniora, 2014 This article aims to describe differences in models and theories of communication and their respective roles. Many students of Communication Studies do not really care because it was considered too elementary. Students tend to focus on the "big things",
Bambang A. S.
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The Journal of Clinical HypertensionHypertension is a multifactorial condition influenced by both genetic and environmental factors. Protein disulfide isomerase family A member 3 (PDIA3) is a key endoplasmic reticulum protein which may contribute to increased blood pressure.
Hongtao Lan +8 more
doaj +1 more source