Results 51 to 60 of about 7,583,872 (228)

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Functional Analysis of the Plain-Error Rule [PDF]

, 1983
In this article, I attempt to do two things at once. First, I attempt to analyze the Supreme Court\u27s jurisdiction to conduct plain-error review of state court decisions.
Spann, Girardeau A
core   +1 more source

An in-depth evaluation of sample and measurement induced influences on static contact angle measurements

Scientific Reports, 2022
Static contact angle measurements are one of the most popular methods to analyze the wetting behavior of materials of any kind. Although this method is readily applicable without the need of sophisticated machinery, the results obtained for the very same
Sarah Marie Lößlein, Rolf Merz, Daniel Wyn Müller, Michael Kopnarski, Frank Mücklich   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

An integrated experimental and analytical approach for the analysis of the mechanical interaction between metal porous scaffolds and bone: implications for stress shielding in orthopedic implants

Frontiers in Bioengineering and Biotechnology
IntroductionMetal porous structures are becoming a standard design feature of orthopedic implants such as joint endoprostheses. The benefits of the pores are twofold: 1) help improve the cementless primary stabilization of the implant by increasing ...
Roberto Ramaglia Amadasi, Giulia Rogati, Erica Liverani, Alberto Leardini, Paolo Caravaggi   +4 more
doaj   +1 more source

Origin of life: β‐sheet amyloid conformers as the primordial functional polymers on the early Earth and their role in the emergence of complex dynamic networks

FEBS Letters, EarlyView.
The amyloid world hypothesis of the origin‐of‐life posits that the first functional polymers on the early Earth were structurally stable cross‐β‐sheet‐based peptide amyloids capable of Darwinian‐like evolution. Peptide amyloids display self‐replication and information transfer, as well as catalytic, adaptive, and evolutive properties.
Carl Peter J. Maury
wiley   +1 more source

A Testability Analysis Framework for Non-Functional Properties

, 2018
This paper presents background, the basic steps and an example for a testability analysis framework for non-functional ...
Felderer, Michael, Feldt, Robert, Marculescu, Bogdan, Neto, Francisco Gomes de Oliveira, Torkar, Richard   +4 more
core   +1 more source

Genetic Regulation of Liver Metabolites and Transcripts Linking to Biochemical-Clinical Parameters

Frontiers in Genetics, 2019
Given the central metabolic role of the liver, hepatic metabolites and transcripts reflect the organismal physiological state. Biochemical-clinical plasma biomarkers, hepatic metabolites, transcripts, and single nucleotide polymorphism (SNP) genotypes of
Siriluck Ponsuksili, Nares Trakooljul, Frieder Hadlich, Karen Methling, Michael Lalk, Eduard Murani, Klaus Wimmers, Klaus Wimmers   +7 more
doaj   +1 more source