Results 311 to 320 of about 563,469 (347)

Towards a semi-automatic functional annotation tool based on decision-tree techniques

, 2008
Jérôme Azé, L. Gentils, Claire Toffano‐Nioche, Valentin Loux, Jean-François Gibrat, Philippe Bessières, C. Rouveirol, Anne Poupon, Christine Froidevaux   +8 more
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Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci

Soenksen J, Chen J, Varshney A, Martin S, MAGIC, Parker SCJ, Morris AP, Asimit JL, Barroso I.   +8 more
europepmc   +1 more source

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Annotated functional decomposition

Computer Applications in Engineering Education, 2021
AbstractExperiences gained from the domain‐specific courses showed that students focus mostly on how to implement solutions and less on what must be considered within the solution. In the case of information systems‐related courses, students focus on system development using specific languages and frameworks while often disregard the required logical ...
Stefan Tubić, Miloš Cvetanović, Zaharije Radivojević, Saša Stojanović   +3 more
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Functional Annotation of Custom Transcriptomes

2022
Many eukaryotic genes can give rise to different alternative transcripts depending on stage of development, cell type, and physiological cues. Current transcriptome-wide sequencing technologies highlight the remarkable extent of this regulation in metazoans and allow for RNA isoforms to be profiled in increasingly small biological samples and with a ...
Fursham Hamid, Kaur Alasoo, Jaak Vilo, Eugene Makeyev   +3 more
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Functional Annotation from Structural Homology

2021
With the nexus of super computing and the biotech revolution, it seems an era of predictive biology through systems biology may be at hand. Modern omics capabilities enable examination of the state of biological system in exquisite detail. The genome, transcriptome, proteome, and metabolome may all be largely knowable, at least for some model systems ...
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Protein Functional Annotation

2019
The deluge of sequencing data needs curated association of structural and functional features to each sequence in the database. Inference of correct annotation is a major problem of sequence analysis. We highlight why it is difficult to solve the annotation task given the little amount of validated information in the database linking sequences ...
Pier Luigi Martelli, Giuseppe Profiti, Rita Casadio   +2 more
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Protein Functional Annotation by Homology

2008
Genome sequencing projects have resulted in a rapid accumulation of predicted protein sequences. With experimentally verified information on protein function lagging far behind, computational methods are used for functional annotation of proteins. Here we describe a number of protocols for protein sequence and structure analysis that can be used to ...
Raja, Mazumder, Sona, Vasudevan, Anastasia N, Nikolskaya   +2 more
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Automatic annotation of protein function

Current Opinion in Structural Biology, 2005
The annotation of protein function at genomic scale is essential for day-to-day work in biology and for any systematic approach to the modeling of biological systems. Currently, functional annotation is essentially based on the expansion of the relatively small number of experimentally determined functions to large collections of proteins.
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Functional genome annotation through phylogenomic mapping

Nature Biotechnology, 2005
Accurate determination of functional interactions among proteins at the genome level remains a challenge for genomic research. Here we introduce a genome-scale approach to functional protein annotation--phylogenomic mapping--that requires only sequence data, can be applied equally well to both finished and unfinished genomes, and can be extended beyond
Balaji S, Srinivasan, Nora B, Caberoy, Garret, Suen, Rion G, Taylor, Radhika, Shah, Farah, Tengra, Barry S, Goldman, Anthony G, Garza, Roy D, Welch   +8 more
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Resources for functional annotation

2008
The continued success of genome sequencing projects has led to an explosion in the availability of sequence data. The Genomes On Line Database (GOLD) currently lists more than 2000 ongoing and completed genome projects, and this number is continuously increasing (Liolios et al. 2008).
A. J. Bridge, A.-Lise Veuthey, N. J. Mulder   +2 more
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