Results 81 to 90 of about 557,186 (345)
Annotating proteins with generalized functional linkages [PDF]
Proceedings of the National Academy of Sciences, 2008 As genome sequencing outstrips the rate of high-quality, low-throughput biochemical and genetic experimentation, accurate annotation of protein function becomes a bottleneck in the progress of the biomolecular sciences. Most gene products are now annotated by homology, in which an experimentally determined function is applied to a similar ...
Richard, Llewellyn, David S, Eisenberg
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circGPA: circRNA functional annotation based on probability-generating functions
BMC Bioinformatics, 2022 AbstractRecent research has already shown that circular RNAs (circRNAs) are functional in gene expression regulation and potentially related to diseases. Due to their stability, circRNAs can also be used as biomarkers for diagnosis. However, the function of most circRNAs remains unknown, and it is expensive and time-consuming to discover it through ...
Petr Ryšavý +2 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Functionally Annotating Regulatory Elements in the Equine Genome Using Histone Mark ChIP-Seq. [PDF]
, 2019 One of the primary aims of the Functional Annotation of ANimal Genomes (FAANG) initiative is to characterize tissue-specific regulation within animal genomes.
Bellone, Rebecca R +9 more
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PANNZER2: a rapid functional annotation web server [PDF]
Nucleic Acids Research, 2018 The unprecedented growth of high-throughput sequencing has led to an ever-widening annotation gap in protein databases. While computational prediction methods are available to make up the shortfall, a majority of public web servers are hindered by practical limitations and poor performance. Here, we introduce PANNZER2 (Protein ANNotation with Z-scoRE),
Medlar Alan, Holm Liisa, Törönen Petri
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An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Best Practices for Comprehensive Annotation of Neuropeptides of Gryllus bimaculatus
Insects, 2023 Genome annotation is critically important data that can support research. Draft genome annotations cover representative genes; however, they often do not include genes that are expressed only in limited tissues and stages, or genes with low expression ...
Takako Mochizuki +8 more
doaj +1 more source
miRDB: An online resource for microRNA target prediction and functional annotations [PDF]
, 2014 functional ...
Wang, Xiaowei, Wong, Nathan
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MycoWiki: Functional annotation of the minimal model organism Mycoplasma pneumoniae [PDF]
, 2022 Christoph Elfmann +6 more
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On gene ontology and function annotation [PDF]
Bioinformation, 2006 The effort of function annotation does not merely involve associating a gene with some structured vocabulary that describes action. Rather the details of the actions, the components of the actions, the larger context of the actions are important issues that are of direct relevance, because they help understand the biological system to which the gene ...
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