Results 31 to 40 of about 769,889 (306)

Functional Role of Dendritic Cell Subsets in Cancer Progression and Clinical Implications

open access: yesInternational Journal of Molecular Sciences, 2020
Dendritic cells (DCs) constitute a complex network of cell subsets with common functions but also with many divergent aspects. All dendritic cell subsets share the ability to prime T cell response and to undergo a complex trafficking program related to ...
A. Del Prete   +9 more
semanticscholar   +1 more source

Myoneurin regulates BMP signaling by competing with Ppm1a for Smad binding

open access: yesiScience, 2022
Summary: A delicate balance of BMP activity is critical for tissue formation and organogenesis. However, the mechanical molecular details in ensuring the proper duration and intensity of BMP signaling have yet to be fully elucidated.
Shuyan Yang   +7 more
doaj   +1 more source

The Unicellular State as a Point Source in a Quantum Biological System. [PDF]

open access: yes, 2016
A point source is the central and most important point or place for any group of cohering phenomena. Evolutionary development presumes that biological processes are sequentially linked, but neither directed from, nor centralized within, any specific ...
Miller, William B, Torday, John S
core   +6 more sources

Tricalbins Are Required for Non-vesicular Ceramide Transport at ER-Golgi Contacts and Modulate Lipid Droplet Biogenesis

open access: yesiScience, 2020
Summary: Lipid composition varies among organelles, and the distinct lipid composition is important for specific functions of each membrane. Lipid transport between organelles, which is critical for the maintenance of membrane lipid composition, occurs ...
Atsuko Ikeda   +5 more
doaj   +1 more source

Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections

open access: yesFrontiers in Immunology, 2019
Natural killer (NK) cells are the major innate effectors primed to eliminate virus-infected and tumor or neoplastic cells. Recent studies also suggest nuances in phenotypic and functional characteristics among NK cell subsets may further permit execution
C. Manickam   +4 more
semanticscholar   +1 more source

Functional Landscape of Dysregulated MicroRNAs in Oral Squamous Cell Carcinoma: Clinical Implications

open access: yesFrontiers in Oncology, 2020
MicroRNA (miRNA) dysregulation is associated with the pathogenesis of oral squamous cell carcinoma (OSCC), and its elucidation could potentially provide information on patient outcome. A growing body of translational research on miRNA biology is focusing
R. Ghosh   +2 more
semanticscholar   +1 more source

Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment

open access: yesiScience, 2022
Summary: Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using
Mariel F. Schwietzer   +8 more
doaj   +1 more source

The case for absolute ligand discrimination : modeling information processing and decision by immune T cells [PDF]

open access: yes, 2015
Some cells have to take decision based on the quality of surroundings ligands, almost irrespective of their quantity, a problem we name "absolute discrimination". An example of absolute discrimination is recognition of not-self by immune T Cells. We show
Altan-Bonnet, Grégoire, François, Paul
core   +2 more sources

SUFU suppresses ferroptosis sensitivity in breast cancer cells via Hippo/YAP pathway

open access: yesiScience, 2022
Summary: Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-dependent lipid peroxidation. Cancer cells differ in their sensitivity to ferroptosis.
Kun Fang   +16 more
doaj   +1 more source

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

open access: yes, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C   +15 more
core   +1 more source

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