Results 51 to 60 of about 716,371 (239)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Meta-Analysis of Exercise Effects on Cognition in Persons with Parkinson’s Disease

NeuroSci
Background: Parkinson’s disease (PD) is a debilitating neurodegenerative disorder affecting millions of people worldwide. PD results in motor and cognitive dysfunction.
Syed O. Ahmad, Dana Stiles, Kaylee Brown, Leah Dillon, Eliza Shroba   +4 more
doaj   +1 more source

Communicative success in spatial dialogue: The impact of functional features and dialogue strategies [PDF]

, 2017
This paper addresses the impact of dialogue strategies and functional features of spatial arrangements on communicative success. To examine the sharing of cognition between two minds in order to achieve a joint goal, we collected a corpus of 24 extended ...
Elena Andonova, Gesa Schole, Gibson J. J., Giles H., Kenny R. Coventry, Schank R., Thora Tenbrink   +6 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Validity of the Japanese Version of the Weekly Calendar Planning Activity (WCPA)-10 on Assessing Executive Function in Patients with Acquired Brain Injury (ABI)

Brain Sciences
Background: The Weekly Calendar Planning Activity (WCPA) is one of the assessments of functional cognition, including executive function, by the cognitive instrumental activities of daily living (C-IADL).
Asako Matsubara, Yasuhiro Higashi, Mio Kawabata, Katsunobu Sugihara   +3 more
doaj   +1 more source

Dual tasking in Parkinson's disease: cognitive consequences while walking [PDF]

, 2017
Published in final edited form as: Neuropsychology. 2017 September; 31(6): 613–623. doi:10.1037/neu0000331.OBJECTIVE: Cognitive deficits are common in Parkinson's disease (PD) and exacerbate the functional limitations imposed by PD's hallmark motor ...
Barthelemy, Olivier J., Cronin-Golomb, Alice, Ellis, Terry D., Neargarder, Sandy, Ren, Xiaolin, Salazar, Robert D., Toraif, Noor   +6 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Cognitive Fatigue, Sleep and Cortical Activity in Multiple Sclerosis Disease. A Behavioral, Polysomnographic and Functional Near-Infrared Spectroscopy Investigation

Frontiers in Human Neuroscience, 2018
Patients with multiple sclerosis (MS) disease frequently experience fatigue as their most debilitating symptom. Fatigue in MS partially refers to a cognitive component, cognitive fatigue (CF), characterized by a faster and stronger than usual development
Guillermo Borragán, Guillermo Borragán, Médhi Gilson, Médhi Gilson, Anne Atas, Anne Atas, Hichem Slama, Hichem Slama, Hichem Slama, Hichem Slama, Andreas Lysandropoulos, Melanie De Schepper, Melanie De Schepper, Philippe Peigneux, Philippe Peigneux   +14 more
doaj   +1 more source

Personalized functional brain network topography is associated with individual differences in youth cognition

Nature Communications, 2023
Individual differences in cognition during childhood are associated with important social, physical, and mental health outcomes in adolescence and adulthood.
Arielle S. Keller, Adam R. Pines, Sheila Shanmugan, Valerie J. Sydnor, Zaixu Cui, Maxwell A. Bertolero, Ran Barzilay, Aaron F. Alexander-Bloch, Nora Byington, Andrew Chen, Gregory M. Conan, Christos Davatzikos, Eric Feczko, Timothy J. Hendrickson, Audrey Houghton, Bart Larsen, Hongming Li, Oscar Miranda-Dominguez, David R. Roalf, Anders Perrone, Alisha Shetty, Russell T. Shinohara, Yong Fan, Damien A. Fair, Theodore D. Satterthwaite   +24 more
doaj   +1 more source