Results 41 to 50 of about 5,950,356 (233)

Functional cognitive disorder: Beyond pseudodementia

Neurology Perspectives
Introduction: Many patients with cognitive symptoms, such as subjective memory complaints, may in fact have functional cognitive disorder. Development: This review explores various aspects of functional cognitive disorder.
D.S. Marín-Medina, P.A. Arenas-Vargas, M. del Pilar Velásquez-Duque, P.M. Bagnati   +3 more
doaj   +1 more source

Self-perceived functional impairment or disability in Delusional Disorder – Case Reports

European Psychiatry, 2022
Introduction Delusional disorder (DD) is a psychotic disorder with an estimated prevalence of less than one percent,traditionally characterized by systematized delusional ideas with no cognitive deterioration.However, some studies have been reporting ...
M.D.R.D.R.F.D. Basto, A. Certo, O. Nombora, A. Horta, E. Mendes, Â. Venâncio   +5 more
doaj   +1 more source

Protocol for a systematic review and meta-analysis of cognitive-behavioural therapy for social anxiety disorder in psychosis [PDF]

, 2014
Background: Social anxiety is among the most prevalent and debilitating affective disturbances manifest in people with psychosis. It is usually accompanied by high levels of depression and leads to significant social disability, lower quality of life ...
Michail, M.; id_orcid, Max Birchwood, Michail, Maria, Maria Michail, Lynda Tait, Birchwood, M., Tait, L., Birchwood, M. J., Tait, Lynda   +8 more
core   +2 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Multidimensional profile of functional cognitive disorders: the experience of the memory clinic in Abidjan, Côte d’Ivoire, sub-Saharan Africa

Frontiers in Neurology
BackgroundFunctional cognitive disorders (FCD) are increasingly recognized but underdiagnosed. In sub-Saharan Africa, the topic is rarely discussed and the data is unknown.
Kouamé Léonard Kouassi, Kouamé Léonard Kouassi, Assi Viviane Yao, N’guessan Yves Constant Broh, N’guessan Yves Constant Broh, Nawa Samuel Yéo, Nawa Samuel Yéo, Ange Stéphane Abbé, Ange Stéphane Abbé, Affoué Marie Roxane Beuseize, Affoué Marie Roxane Beuseize, Ahya Nancy Tanya Essoin-De Souza, Ahya Nancy Tanya Essoin-De Souza, Ismaïla Diakité, Ismaïla Diakité, Mariam Doumbia-Ouattara, Mariam Doumbia-Ouattara   +16 more
doaj   +1 more source

Dysfunction between dorsal caudate and salience network associated with impaired cognitive flexibility in obsessive-compulsive disorder: A resting-state fMRI study

NeuroImage: Clinical, 2019
Background: Impaired cognitive flexibility has been implicated in the genetic basis of obsessive-compulsive disorder (OCD). Recent endophenotype studies of OCD showed neural inefficiency in the cognitive control network and interference by the limbic ...
Hirofumi Tomiyama, Tomohiro Nakao, Keitaro Murayama, Kiyotaka Nemoto, Keisuke Ikari, Satoshi Yamada, Masumi Kuwano, Suguru Hasuzawa, Osamu Togao, Akio Hiwatashi, Shigenobu Kanba   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source