Results 71 to 80 of about 5,950,356 (233)

Risk, Precipitating, and Perpetuating Factors in Functional Neurological Disorder: A Systematic Review Across Clinical Subtypes

open access: yesBrain Sciences
Background: Functional Neurological Disorder (FND) encompasses conditions with neurological symptoms inconsistent with structural pathology, arising instead from complex interactions between psychological, biological, and social factors.
Ioannis Mavroudis   +8 more
doaj   +1 more source

Default mode network connectivity as a function of familial and environmental risk for psychotic disorder.

open access: yesPLoS ONE, 2015
BackgroundResearch suggests that altered interregional connectivity in specific networks, such as the default mode network (DMN), is associated with cognitive and psychotic symptoms in schizophrenia.
Sanne C T Peeters   +8 more
doaj   +1 more source

Cognitive behavioral therapy and functional impairment in obsessive–Compulsive disorder

open access: yesIndian Journal of Social Psychiatry, 2019
Background: Obsessive–compulsive disorder (OCD) is characterized by the presence of obsessions and compulsions and has a lifetime prevalence of around 2%–3%.
Laxmi Narayan Rathore, Jai Prakash
doaj   +1 more source

Diagnosis and treatment of functional cognitive disorders

open access: yes
An increasing number of individuals are seeking memory services due to concerns about cognitive decline. Many of them have a potentially reversible, yet disabling, functional cognitive disorder. This condition has been recognised and better characterised
Cabreira, Verónica Raquel Alheia
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Corrigendum: Toward a possible trauma subtype of functional neurological disorder: impact on symptom severity and physical health

open access: yesFrontiers in Psychiatry, 2023
Sara Paredes-Echeverri   +4 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Letter to the Editor – Towards an Outpatient Model of Care for Motor Functional Neurological Disorders: A Neuropsychiatric Perspective [Letter]

open access: yesNeuropsychiatric Disease and Treatment, 2021
Lars de Vroege, 1, 2 Anne Vergeest, 1, 2 Willem Johan Kop 1, 3 1Clinical Center of Excellence for Body, Mind and Health, GGz Breburg, Tilburg, the Netherlands; 2Tilburg School of Behavioral and Social Sciences, Tranzo Department, Tilburg University ...
de Vroege L, Vergeest A, Kop WJ
doaj  

Cognitive and Functional Assessment of Psychosis Stratification Study (CoFAPSS): Rationale, Design, and Characteristics

open access: yesFrontiers in Psychiatry, 2018
Prediction of treatment response and illness trajectory in psychotic disorders including schizophrenia, bipolar affective disorder, schizoaffective disorder, and psychotic depression is difficult due to heterogeneity in presentation and outcome ...
Scott R. Clark   +6 more
doaj   +1 more source

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