Results 51 to 60 of about 110,424 (352)
Advanced Science, EarlyView.Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye +7 more
wiley +1 more source
Gut Microbiota and Functional Constipation: Recent Advances in Pathogenesis and Nutritional Interventions [PDF]
Shipin KexueWith the acceleration of population aging, the problem of functional constipation has become increasingly prominent, significantly affecting the quality of life of the elderly.
DUAN Hao, LIU Gaigai, LU Jiamin, LI Yang, CHANG Xinyue, YANG Tianyu, BAO Shuyuan, SONG Wei, YAN Wenjie
doaj +1 more source
Functional bowel disease : a challenging frontier in gastroenterology [PDF]
, 1999 The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
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Advanced Science, EarlyView.This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu +6 more
wiley +1 more source
Frontiers in NutritionFunctional constipation is a common gastrointestinal health issue among the aging population. Dietary fiber supplementation is widely recognized as a first-line strategy for constipation.
Liya Mo +6 more
doaj +1 more source
Somatic Comorbidity in Chronic Constipation: More Data from the GECCO Study
Gastroenterology Research and Practice, 2016 Background. Comorbidity in chronic constipation has rarely been investigated, despite the fact that constipation can occur as one symptom in a number of neurological, systemic, and other nonintestinal and intestinal disorders. Methods.
Paul Enck +4 more
doaj +1 more source
Wearable Metamaterials with Embodied Intelligence for Programmable Control of Human Limbs Tremor
Advanced Intelligent Systems, EarlyView.Resulting from alternating muscle contractions, tremors can severely limit human ability to perform everyday tasks like walking or talking, due to their disruptive nature. Medication and surgery may not always effectively address tremor control. A wearable device embodying programmable smart metamaterials with adaptable intelligence to meet the demand ...
Braion Barbosa de Moura +2 more
wiley +1 more source
Current views on functional constipations in infants
Zdorovʹe Rebenka, 2018 This article states that about 3–13 % of infants display symptoms of functional constipation. These symptoms may cause parents to worry, and drive them to seek medical advice.
О.S. Nyankovska
doaj +1 more source
The Knowledge and Therapeutic Approach of Paediatrician on Functional Constipation
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022 Background: Functional constipation is one of the most common functional gastrointestinal disorders in children under 4 years of age. The Rome IV Criteria have standardized diagnostic criteria for functional constipation.
Brahmantyo Ardhi Wicaksono +4 more
doaj +1 more source
Polyethylene glycol and prevalence of colorectal adenomas : Population-based study of 1165 patients undergoing colonoscopy [PDF]
, 2006 Background and aim — Dietary polyethylene glycol (PEG) is extraordinarily potent in the chemoprevention of experimental colon carcinogenesis. PEG is used to treat constipation in France and in the USA. French laxatives include Forlax® (PEG4000), Movicol®
Barbieux, Jean-Pierre +7 more
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