Results 51 to 60 of about 112,346 (350)

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Gut Microbiota and Functional Constipation: Recent Advances in Pathogenesis and Nutritional Interventions [PDF]

Shipin Kexue
With the acceleration of population aging, the problem of functional constipation has become increasingly prominent, significantly affecting the quality of life of the elderly.
DUAN Hao, LIU Gaigai, LU Jiamin, LI Yang, CHANG Xinyue, YANG Tianyu, BAO Shuyuan, SONG Wei, YAN Wenjie
doaj   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Functional bowel disease : a challenging frontier in gastroenterology [PDF]

, 1999
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core  

LARS-like symptoms in the general population may suggest the significance of postoperative functional problems and emotional implications of rectal surgery [PDF]

, 2019
Background & Aim. Sphincter-saving rectal surgery is prone to cause changes in bowel function associated with Low Anterior Resection Syndrome (LARS). Our aim was to assess LARS-like symptoms within a population of 50-80-year old in order to understand ...
Axinia, Iulia, Baciu, Iustina, Bujor, Narcis, Crudu, Andreea, Diaconu, Anca, Dimofte, Mihail G, Frunza, Tudor-Cristian, Hulubencu, Andreea, Jalobceastai, Ioana, Livenschi, Lucia F, Lunca, Sorinel, Mocanu, Cezar V, Nicolaiev, Claudiu A, Tibirna, Malina, Valasciu, Emilia   +14 more
core   +2 more sources

Somatic Comorbidity in Chronic Constipation: More Data from the GECCO Study

Gastroenterology Research and Practice, 2016
Background. Comorbidity in chronic constipation has rarely been investigated, despite the fact that constipation can occur as one symptom in a number of neurological, systemic, and other nonintestinal and intestinal disorders. Methods.
Paul Enck, Johannes Leinert, Menno Smid, Thorsten Köhler, Juliane Schwille-Kiuntke   +4 more
doaj   +1 more source

Current views on functional constipations in infants

Zdorovʹe Rebenka, 2018
This article states that about 3–13 % of infants display symptoms of functional constipation. These symptoms may cause parents to worry, and drive them to seek medical advice.
О.S. Nyankovska
doaj   +1 more source

The Knowledge and Therapeutic Approach of Paediatrician on Functional Constipation

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: Functional constipation is one of the most common functional gastrointestinal disorders in children under 4 years of age. The Rome IV Criteria have standardized diagnostic criteria for functional constipation.
Brahmantyo Ardhi Wicaksono, Fransesco B Hubert Jonathan, Agus Tini Sridevi, Dewi Friska, Badriul Hegar   +4 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Tapentadol extended release for the management of chronic neck pain [PDF]

, 2017
BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core   +1 more source