Results 181 to 190 of about 412,466 (343)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Elebsiran and pegylated-IFNα: Progress toward a functional cure for chronic hepatitis B. [PDF]

JHEP Rep
Battistella S, Protzer U, Forns X.
europepmc   +1 more source

Maintenance Mechanism of Chronic HBV Infection and the Strategy for Functional Cure [PDF]

Ziyuan Ma, Lili Wu, Fengmin Lu
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Efficacy of NAs in combination with Peg-IFN for functional cure in patients with CHB: a meta-analysis of RCTs. [PDF]

Ann Med
Zhang Y, Zhang Z, Li X, Cao W, Wang S, Deng W, Wei X, Yao L, Xie Y, Li M.   +9 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Learning from nature: HIV elite controllers as blueprints for a functional cure. [PDF]

Virol J
Kalidasan V, Theva Das K.
europepmc   +1 more source

Functional Cure of SIVagm Infection in Rhesus Macaques Results in Complete Recovery of CD4+ T Cells and Is Reverted by CD8+ Cell Depletion

, 2011
Ivona Pandrea, Thaidra Gaufin, Rajeev Gautam, Jan Kristoff, Daniel M. Mandell, David C. Montefiori, Brandon F. Keele, Ruy M. Ribeiro, Ronald S. Veazey, Cristian Apetrei   +9 more
openalex   +2 more sources

Correlation between HBV core-related antigen and the new quantitative IGG anti-core in treated caucasian HBeAg-negative patients and inactive carriers with and without a functional cure

, 2020
Alessandro Loglio, F. Facchetti, Elisa Farina, Nicoletta Nandi, Alberto Perego, Riccardo Perbellini, Sara Uceda Renteria, Marta Borghi, R. Soffredini, Corinna Orsini, G. Lunghi, Ferruccio Ceriotti, Pietro Lampertico   +12 more
openalex   +1 more source

Adeno-associated virus-vectored delivery of HIV biologics: the promise of a “single-shot” functional cure for HIV infection

, 2023
P. Hahn, Maurício A. Martins
openalex   +1 more source