Results 201 to 210 of about 412,466 (343)
Functionally Graded Materials: controlling the polymer curing
FGMs (Functionally Graded Materials) have gradients of mechanical properties depending on the position. FGMs are inspired in nature and recognised due to their superiority and application flexibility. Exceptional materials capable of combining harder and softer zones. Exhibiting high performance tensile properties either for fracture stress strength or
openaire +2 more sources
Checkpoint blockade and the stem‐like T cell trade‐off
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
An HBV-Derived Peptide Poly6 as a Novel Candidate for Functional Cure Via IFN-I-Mediated Epigenetic Regulation of cccDNA. [PDF]
Jang J +5 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Host restriction factors and p17-Driven inflammaging in HIV-1: From molecular pathogenesis to functional cure. [PDF]
Nitsotolis T +8 more
europepmc +1 more source
Development of flax oil-based biopolymer for biocomposites [PDF]
Dhakal, Hom +4 more
core +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source

