Results 211 to 220 of about 3,345,035 (259)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Functional data analysis of fNIRS data

open access: yes, 2019
Bartkus, Karolis   +2 more
openaire   +1 more source

Functional analysis of glaucoma data

Statistics in Medicine, 2013
We refer glaucoma to a category of eye disorders often associated with a dangerous buildup of intraocular pressure (IOP), which can damage the eyes’ optic nerve that transmits visual information to the brain. Because IOP changes over time, it is a function of time, and it is an advantage that we analyze the phenomenon using functional data analysis. In
Hosseini-Nasab, Mohammad   +1 more
openaire   +3 more sources

FUNCTIONAL ANALYSIS FOR PARAMETRIC FAMILIES OF FUNCTIONAL DATA

International Journal of Bifurcation and Chaos, 2012
Assuming a Parametric Family of Functional Data, the problem of computing summary statistics of the same functional form is investigated. The central idea is to compile the statistics on the parameters instead of on the functions themselves. With the hypothesis of a monotonic dependence from parameters, we highlight the special features of this ...
DE SANCTIS, Angela Anna   +1 more
openaire   +2 more sources

Functional Analysis of Metabolomics Data

2016
Metabolomics aims at characterizing the repertory of small chemical compounds in a biological sample. As it becomes more massive and larger sets of compounds are detected, a functional analysis is required to convert these raw lists of compounds into biological knowledge.
Mónica, Chagoyen   +2 more
openaire   +2 more sources

A Functional Model for Data Analysis

2006
We present a functional model for the analysis of large volumes of detailed transactional data, accumulated over time. In our model, the data schema is an acyclic graph with a single root, and data analysis queries are formulated using paths starting at the root.
openaire   +1 more source

Home - About - Disclaimer - Privacy