Results 211 to 220 of about 3,345,035 (259)
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
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Functional analysis of glaucoma data
Statistics in Medicine, 2013We refer glaucoma to a category of eye disorders often associated with a dangerous buildup of intraocular pressure (IOP), which can damage the eyes’ optic nerve that transmits visual information to the brain. Because IOP changes over time, it is a function of time, and it is an advantage that we analyze the phenomenon using functional data analysis. In
Hosseini-Nasab, Mohammad +1 more
openaire +3 more sources
FUNCTIONAL ANALYSIS FOR PARAMETRIC FAMILIES OF FUNCTIONAL DATA
International Journal of Bifurcation and Chaos, 2012Assuming a Parametric Family of Functional Data, the problem of computing summary statistics of the same functional form is investigated. The central idea is to compile the statistics on the parameters instead of on the functions themselves. With the hypothesis of a monotonic dependence from parameters, we highlight the special features of this ...
DE SANCTIS, Angela Anna +1 more
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Functional Analysis of Metabolomics Data
2016Metabolomics aims at characterizing the repertory of small chemical compounds in a biological sample. As it becomes more massive and larger sets of compounds are detected, a functional analysis is required to convert these raw lists of compounds into biological knowledge.
Mónica, Chagoyen +2 more
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A Functional Model for Data Analysis
2006We present a functional model for the analysis of large volumes of detailed transactional data, accumulated over time. In our model, the data schema is an acyclic graph with a single root, and data analysis queries are formulated using paths starting at the root.
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