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Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
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Functional analysis of glaucoma data
Statistics in Medicine, 2013We refer glaucoma to a category of eye disorders often associated with a dangerous buildup of intraocular pressure (IOP), which can damage the eyes’ optic nerve that transmits visual information to the brain. Because IOP changes over time, it is a function of time, and it is an advantage that we analyze the phenomenon using functional data analysis. In
Hosseini-Nasab, Mohammad +1 more
openaire +3 more sources
FUNCTIONAL ANALYSIS FOR PARAMETRIC FAMILIES OF FUNCTIONAL DATA
International Journal of Bifurcation and Chaos, 2012Assuming a Parametric Family of Functional Data, the problem of computing summary statistics of the same functional form is investigated. The central idea is to compile the statistics on the parameters instead of on the functions themselves. With the hypothesis of a monotonic dependence from parameters, we highlight the special features of this ...
DE SANCTIS, Angela Anna +1 more
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Functional Analysis of Metabolomics Data
2016Metabolomics aims at characterizing the repertory of small chemical compounds in a biological sample. As it becomes more massive and larger sets of compounds are detected, a functional analysis is required to convert these raw lists of compounds into biological knowledge.
Mónica, Chagoyen +2 more
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Functional Data Analysis for Sparse Functional Data
2018With the development of science and modern technology, more and more data are being collected continuously over a time interval in various disciplines, such as public health, biology, medicine and finance. Such data can be viewed as ``functional data". Functional data analysis (FDA), which deals with the analysis and theory of functional data, has been
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A Functional Model for Data Analysis
2006We present a functional model for the analysis of large volumes of detailed transactional data, accumulated over time. In our model, the data schema is an acyclic graph with a single root, and data analysis queries are formulated using paths starting at the root.
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Repeated measures analysis for functional data
Computational Statistics & Data Analysis, 2011zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Pablo Martínez-Camblor, Norberto Corral
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