Results 111 to 120 of about 481,094 (301)
An M-Estimator for Tail Dependence in Arbitrary Dimensions [PDF]
Consider a random sample in the max-domain of attraction of a multivariate extreme value distribution such that the dependence structure of the attractor belongs to a parametric model.
Krajina, A., Segers, J., Einmahl, J.H.J.
core +1 more source
A Kendall correlation coefficient for functional dependence [PDF]
, 2013 Measuring dependence is a basic question when dealing with functional observations. The usual correlation for curves is not robust. Kendall's coefficient is a natural description of dependence between finite dimensional random variables.
Lillo Rodríguez, Rosa Elvira +4 more
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A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. [PDF]
, 2011 Several genome-wide association studies (GWASs) reported tens of risk genes for alcohol dependence, but most of them have not been replicated or confirmed by functional studies. The present study used a GWAS to search for novel, functional and replicable
Chiang-Shan R Li +26 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An M-estimator of multivariate tail dependence. [PDF]
AN M-ESTIMATOR OF TAIL DEPENDENCE. Extreme value theory is the part of probability and statistics that provides the theoretical background for modeling events that almost never happen.
Krajina, A.
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Reward responsivity and the development of nicotine dependence [PDF]
, 2008 Different theories have been proposed to explain the development of nicotine dependence. Some theories suggest that nicotine has direct reinforcing properties, either positive or negative.
Kalamboka, Natasha
core
The Budget-Constrained Functional Dependency
CoRR, 2015 Armstrong's axioms of functional dependency form a well-known logical system that captures properties of functional dependencies between sets of database attributes. This article assumes that there are costs associated with attributes and proposes an extension of Armstrong's system for reasoning about budget-constrained functional dependencies in such ...
Pavel Naumov, Jia Tao 0001
openaire +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Introduction to the College on Problems of Drug Dependence Special Issue: Contemporary Advances in Opioid Neuropharmacology [PDF]
, 2010 Opioid receptors are critical therapeutic targets for medications development relevant to the treatment of drug dependence and pain. With recent advances in molecular neurobiology, it has become evident that the functional activity of opioid receptors ...
Walsh, Sharon L +2 more
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