Results 101 to 110 of about 5,452,648 (239)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Pathophysiology of Functional Dyspepsia

Journal of Nippon Medical School, 2011
Functional dyspepsia is a highly prevalent and heterogeneous disorder. Functional dyspepsia involves many pathogenic factors, such as gastric motility disorders, visceral hypersensitivity, psychological factors, Helicobacter pylori infection, and excessive gastric acid secretion.
Futagami, Seiji, Shimpuku, Mayumi, Yin, Yan, Shindo, Tomotaka, Kodaka, Yasuhiro, Nagoya, Hiroyuki, Nakazawa, Shoko, Fujimoto, Mayumi, Izumi, Nikki, Ohishi, Noriko, Kawagoe, Tetsuro, Horie, Akane, Iwakiri, Katsuhiko, Sakamoto, Choitsu   +13 more
openaire   +3 more sources

Hubungan Derajat Keasaman Cairan Lambung dengan Derajat Dispepsia pada Pasien Dispepsia Fungsional

Jurnal Kesehatan Andalas, 2016
AbstrakHipersekresi asam lambung dianggap penting sebagai salah satu mekanisme patologis dispepsia fungsional. Hipersekresi asam lambung dapat meningkatkan sekresi pepsin yang dapat menimbulkan kerusakan mukosa lambung pada dispepsia fungsional.
Emil Prasetyo Muhammad, Arina Widya Murni, Delmi Sulastri, Saptino Miro   +3 more
doaj  

The role of diet in the overlap between gastroesophageal reflux disease and functional dyspepsia

The Turkish Journal of Gastroenterology, 2016
Background/Aims: The prevalence of functional dyspepsia partially overlaps with gastroesophageal reflux disease (GERD), and this suggests common pathogenic mechanisms. The role of diet in these conditions is still under investigation.
Ioan Chirila, Ionela Daniela Morariu, Oana Bogdana Barboi, Vasile Liviu Drug   +3 more
doaj   +1 more source

Postelectroacupuncture Fecal Microbiota Transplantation (post‐EA FMT) Regulates Gastrointestinal Hormones in Functional Dyspepsia Rats Is Associated With Modulation of the Intestinal Microbiota‐Bile Acid Metabolic Pathway

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Electroacupuncture (EA) reshapes intestinal flora; whether post‐EA fecal microbiota transplantation (post‐EA FMT) regulates gastrointestinal hormones via the gut microbiota–bile acid (BA) pathway remains unclear. Methods Sham EA (SEA) served as control. Gastrointestinal hormones/motility were assessed post‐EA.
Yong‐Li Han, Dong‐Fang Shang, Juli Tang, Dong‐Dong Yu, Liang‐Yu Zhang, Jing Zhou, Qing‐Bo Wang   +6 more
wiley   +1 more source

The Effect of Central Sensitization on Long‐Term Prognosis and Comorbidity Levels in Temporomandibular Disorders: A Prospective Longitudinal Study

Journal of Oral Rehabilitation, EarlyView.
Higher central sensitization‐related symptoms levels based on the Central Sensitization Inventory (CSI) predict greater psychological distress, sleep disturbance, autonomic dysfunction and reduced response to long‐term conservative treatment in temporomandibular disorders.
Seok Jin Lee, Youngwoo Chun, Jung Hwan Jo, Prangtip Potewiratnanond, Ji Woon Park   +4 more
wiley   +1 more source

GENERAL PRACTITIONERS KNOWLEDGE REGARDING FUNCTIONAL DYSPEPSIA

Pakistan Journal of Medicine and Dentistry, 2019
Background: Most researches on Gastrointestinal (GI) disorders are conducted in secondary health care settings, yet majority patients present at a primary health care level.
Farah Ahmad, Syed Hasan Danish, Ahsan Ashfaq, Sharmeen Naz, Rao Abdul Basit   +4 more
doaj  

Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond

Obesity Reviews, EarlyView.
ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–effect relationship between OAO, CVD, and other systemic complications ...
Wael Almahmeed, Juan S. Barajas‐Gamboa, Mohammad Zubaid, Ebaa Al Ozairi, Abdullah Shehab, Khalid Al‐Rasadi, Charbel Abi Khalil, Noor Al Busaidi, Fahad Al Sindi, Zuhier Awan, Tomader Ali, Khaldoon Al‐Humood, Fatheya Al Awadi, Mohammed Al Hadad, Manal Al Kindi, Khalid Al Habib, Khalid Al Waili, Maryam Alsaeed, Adel Tash, Hani Sabbour   +19 more
wiley   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

Gastritol in Correction of Clinical Symptoms and Disorders of Gastric Secretion in Functional Dyspepsia in Children

Zdorovʹe Rebenka, 2013
The article presents the diagnostic criteria for functional dyspepsia, postprandial syndrome, epigastric pain syndrome. The findings on Gastritol effectiveness in the correction of clinical symptoms of functional dyspepsia in children had been described.
Yu.V. Belousov, Ye.B. Ganziy
doaj   +1 more source