Results 81 to 90 of about 71,517 (254)

Addition theorems for Ck real functions and applications in ordinary differential equations

, 2020
20 pages, 7 ...
Crespo, Francisco, Rebollo-perdomo, Salomón, Zapata, Jorge L.   +2 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

On Certain Multiple Series with Functional Equation in a Totally Real Number Field I

Tokyo Journal of Mathematics, 1995
Let \(K\) be a totally real field of algebraic numbers of degree \(n\), let \(A,B\) be ideals of its ring of integers, choose a positive integer \(k\) and let \(\tau_1,\dots,\tau_n\) be non-zero complex numbers whose arguments lie in the interval \((-\pi/2k,\pi/2k)\). For \(l\) prime to \(k\) put \[ M(\tau;A,B;k,l)=\sum_\mu{1\over| N(\mu)| }\sum_{0\neq\
openaire   +3 more sources

The functional equation of zeta distributions associated with formally real Jordan algebras

Tohoku Mathematical Journal, 1984
Let V be a formally real simple Jordan algebra over \({\mathbb{R}}\) and let N be the reduced norm of V. G denotes the structure group of V, \(G^ 0\) is the connected component of the identity of G. The set of real invertible elements from V is decomposed into the union of \(G^ 0\)-orbits \(\prod_{i}\Omega_ i\). The zeta distribution on V is a map \[ f\
Satake, I., Faraut, J.
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Functional Equations and Combinatorial Constructions of Pathological Functions in Real Analysis

This paper explores the construction of continuous nowhere differentiable functions, a cornerstone in real analysis since Weierstrass’ 1872 example. Two frameworks are developed and analyzed rigorously: (1) a functional-equation approach leading to generalized Weierstrass-type functions, and (2) a combinatorial construction based on binary digit ...
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Approach for the Calculation of Transmission Ratios and Their Errors in 4-Bar Mechanisms, Considering the Precision Variations by Dimensional Tolerances

AppliedMath
This paper presents research and theoretical development of a mathematical model that, first, allows us to understand how the positional exactitude of the output link of a four-bar mechanism depends on the manufacturing dimensional tolerances.
Javier Flores Méndez, Gustavo M. Minquiz, Alfredo Morales-Sánchez, Mario Moreno, Zaira Jocelyn Hernández Simón, José Alberto Luna López, Francisco Severiano Carrillo, Luis Hernández Martínez, Nancy E. González Sierra, Ana Cecilia Piñón Reyes   +9 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source