Results 131 to 140 of about 9,169,303 (329)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Functional equivalence and the new Dutch translation project

open access: yesActa Theologica, 2002
In this article De Blois and Mewe demonstrate how functional-equivalent principles had been originally defined with regard to the Netherlands Bible Society’s Nieuwe Bijbelvertaling (New Bible Translation) and had to be redefined in light of the need for
K. F. de Blois, T. Mewe
doaj   +1 more source

Living shorelines achieve functional equivalence to natural fringe marshes across multiple ecological metrics. [PDF]

open access: yesPeerJ, 2021
Isdell RE   +6 more
europepmc   +1 more source

COMPUTING EQUIVALENT TABULAR FUNCTIONS

open access: yesDemonstratio Mathematica, 2002
Summary: Tabular functions were invented to form a formal framework for normal and inverted function tables used in documenting complex software systems. They are defined as maps on finite partitions of a given nonempty set \(X\) with values in a set of function symbols.
openaire   +2 more sources

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Adult Equivalence Scales, Inequality and Poverty in New Zealand [PDF]

open access: yes
This paper examines the sensitivity of inequality and poverty measures to the choice of adult equivalence scales and the type of income unit examined.
Catherine Sleeman, John Creedy
core  

Conference Report: How Much Culture is Psychology Able to Deal With? Conference "The 100 Years of the German Society of Psychology"

open access: yesForum: Qualitative Social Research, 2005
The 44th Conference of the German Society of Psychology in Göttingen was the first forum for cultural psychologists to criticize the praxis of cross-cultural research in psychology and the methods and methodologies that are used. These problems have been
Lars Allolio-Näcke
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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