Results 111 to 120 of about 535,015 (301)

EFFECTS OF A ONE‐YEAR EXERCISE PROGRAM  ON MUSCLE POWER IN OLDER WOMEN [PDF]

open access: yesBulletin of the Transilvania University of Braşov: Series IX Sciences of Human Kinetics, 2018
Aging is accompanied by a loss of muscle mass, the quality of which clearly affects the quality of life in older adults and their ability to perform daily routines. Appropriately, selected physical intervention may significantly influence muscle atrophy.
L.TLUČÁKOVÁ, V. BEBČÁKOVÁ
doaj  

In-vivo mutation rates and fitness landscape of HIV-1

open access: yes, 2016
Mutation rates and fitness costs of deleterious mutations are difficult to measure in vivo but essential for a quantitative understanding of evolution. Using whole genome deep sequencing data from longitudinal samples during untreated HIV-1 infection, we
Albert, Jan   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Predator confusion is sufficient to evolve swarming behavior

open access: yes, 2013
Swarming behaviors in animals have been extensively studied due to their implications for the evolution of cooperation, social cognition, and predator-prey dynamics.
Adami, Christoph   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Functional and motor fitness of 7-8 form pupils as factor of health improvement

open access: yesJournal of Education, Health and Sport, 2017
Ivashchenko Olga, Kuznetsova Olena, Zukow Walery. Functional and motor fitness of 7-8 form pupils as factor of health improvement. Journal of Education, Health and Sport. 2016;6(11):325-328. eISSN 2391-8306.
Olga Ivashchenko   +2 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Explanation of the Structural-functional Challenges of Comprehensive Health Centers in Babol City, Iran, Based on the Guidelines of the World Health Organization’s Elderly-friendly Centers

open access: yesSālmand, 2023
Objectives Primary care is the first main interface of health services for the elderly to maintain and improve their health. Therefore, it is essential to evaluate the appropriateness of the way to provide services for this population group, which is one
Fatemeh Soleimani Kebria   +6 more
doaj  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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