Results 71 to 80 of about 535,015 (301)

The Comparison of Dual-Tasking and Functional Fitness in Older Females [PDF]

open access: yes, 2016
Context: America’s aging population is growing faster than ever, resulting in increasing challenges for healthcare providers and caregivers. Over 33% of adults aged 65 and older fall annually, and falls are the number one cause of injury-related death in
Engler, Anna
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Influence of estimated training status on anti and pro-oxidant activity, nitrite concentration, and blood pressure in middle-aged and older women [PDF]

open access: yes, 2017
The purpose of this study was to compare the association between anti and pro-oxidant activity, nitrite concentration, and blood pressure (BP) in middle-aged and older women with different levels of estimated training status (TS). The sample consisted of
Amaral, Sandra L.   +8 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Diffusion-based neuromodulation can eliminate catastrophic forgetting in simple neural networks

open access: yes, 2017
A long-term goal of AI is to produce agents that can learn a diversity of skills throughout their lifetimes and continuously improve those skills via experience. A longstanding obstacle towards that goal is catastrophic forgetting, which is when learning
Clune, Jeff, Velez, Roby
core   +2 more sources

Allelic heterogeneity and trade-off shape natural variation for response to soil micronutrient [PDF]

open access: yes, 2012
Peer reviewedPublisher ...
Andreatta, Matthew   +6 more
core   +6 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Natural process – Natural selection [PDF]

open access: yes, 2007
Life is supported by a myriad of chemical reactions. To describe the overall process we have formulated entropy for an open system undergoing chemical reactions.
Annila, Arto
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Measuring the Impact of COVID-19 on Young Adult Functional Capacity: A Comparative Study of Walking and Step Endurance Tests

open access: yesPhysical Education Theory and Methodology
Objectives. This study aimed to evaluate and compare the functional capacity of young adults recovering from COVID-19 using the 6-Minute Walk Test (6MWT) and 2-Minute Step Test (2MST), focusing on cardiovascular parameters, and to examine correlations ...
Patchareeya Amput   +7 more
doaj   +1 more source

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