Results 81 to 90 of about 4,222,887 (283)

Sensory Impairments among Canadians 55 years and Older: An Analysis of 1986 and 1991 Health and Activity Limitation Survey [PDF]

It has been well established that increasing age is associated with worsening health and decreasing functional ability among seniors, including conditions that lead to hearing and seeing impairments.
Larry W. Chambers, Steven Dukeshire, Joan Lindsay, Parminder Raina   +3 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reference values of hand-grip dynamometry and the relationship between low strength and mortality in older Chileans

Clinical Interventions in Aging, 2018
Lydia Lera, Cecilia Albala, Bárbara Leyton, Carlos Márquez, Bárbara Angel, Rodrigo Saguez, Hugo Sánchez Public Health Nutrition Unit, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile Aim: This
Lera L, Albala C, Leyton B, Márquez C, Angel B, Saguez R, Sánchez H   +6 more
doaj  

Association between depressive syndrome and visual complaints among elderly caregivers

Jornal Brasileiro de Psiquiatria
Objectives To determine depressive syndrome in community-dwelling elderly caregivers; and to test the association between such syndrome and both visual complaints (VC) and aspects of care.
Allan Gustavo Brigola, Mayara Caroline Barbieri, Bruna Moretti Luchesi, Eliane da Silva Grazziano, Regimar Carla Machado, Giselle Dupas, Sofia Cristina Iost Pavarini   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

IMPACT OF FEDERAL ACREAGE LIMITATION POLICY ON WESTERN IRRIGATED AGRICULTURE [PDF]

Long-Run Average Cost Curves were developed for 18 Federal irrigation districts indicating in general constant cost industry. Conclusions were that InteriorÂ’s acreage limitation policy would cause no appreciable loss in economic efficiency nor an ...
Moore, Charles V.
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Ageing under unequal circumstances: a cross-sectional analysis of the gender and socioeconomic patterning of functional limitations among the Southern European elderly

International Journal for Equity in Health, 2017
Background In a context of population ageing, it is a priority for planning and prevention to understand the socioeconomic (SE) patterning of functional limitations and its consequences on healthcare needs.
Manuel Serrano-Alarcón, Julian Perelman
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Reliability and validity of the Buruli ulcer functional limitation score questionnaire [PDF]

, 2005
The reliability and validity of the earlier developed Buruli ulcer functional limitation score (BUFLS) questionnaire was assessed. Of 638 former Buruli ulcer patients (of 678 individuals examined), sufficient items on daily activities (>= 13 of the 19)
van der Werf, T.S., Gbovi, J., Klutse, E.Y., Johnson, R.C., Dijkstra, P.U., Zijlstra, I., Zinsou, C., Ampadu, E.O., van Roest, M.H., Stienstra, Y., Etuaful, S., Beets, M., van der Graaf, W.T., van Wezel, M.J.   +13 more
core   +7 more sources