Results 101 to 110 of about 2,526,308 (267)

Corrigendum: A compact multi-functional model of the rabbit atrioventricular node with dual pathways. [PDF]

Front Physiol, 2023
Ryzhii M, Ryzhii E.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Functional models for Nevanlinna families [PDF]

Opuscula Mathematica, 2008
The class of Nevanlinna families consists of \(\mathbb{R}\)-symmetric holomorphic multivalued functions on \(\mathbb{C} \setminus \mathbb{R}\) with maximal dissipative (maximal accumulative) values on \(\mathbb{C}_{+}\) (\(\mathbb{C}_{-}\), respectively)
Jussi Behrndt, Seppo Hassi, Henk de Snoo
doaj  

A compact multi-functional model of the rabbit atrioventricular node with dual pathways. [PDF]

Front Physiol, 2023
Ryzhii M, Ryzhii E.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

DEVELOPMENT OF A GENERALIZED FUNCTIONAL MODEL OF THE DUAL MAINTENANCE OF VOCATIONAL TRAINING OF FUTURE ENGINEERS-TEACHERS OF A COMPUTER PROFILE

Ìнформаційні технології в освіті, 2015
The approaches are analyzed and the development of a generalized functional model of the dual content of training of future engineers-teachers of computer type is implemented in the article.
V. Khomenko
doaj  

Modified TPP-MoS₂ QD Blend as a Bio-Functional Model for Normalizing Microglial Dysfunction in Alzheimer's Disease. [PDF]

Neurol Int, 2023
Alomari OA, Qusti S, Balgoon M, Aljoud F, Alamry KA, Hussein MA.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Research of efficiency of introduction structural functional case of the system of physical preparation of servicemen of service safety of Ukraine frame [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
The factors of increase of specialist's level of professional administrative jurisdiction are considered to operatively-battle and to physical preparation.
Konovalov V.V.
doaj  

Rethinking the framework constructed by counterfactual functional model. [PDF]

Appl Intell (Dordr), 2022
Wang C, Liu L, Sun S, Wang W.
europepmc   +1 more source