Results 81 to 90 of about 6,198,061 (298)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Transfer matrix functional relations for the generalized tau_2(t_q) model
The $N$-state chiral Potts model in lattice statistical mechanics can be obtained as a ``descendant'' of the six-vertex model, via an intermediate ``$Q$'' or ``$\tau_2 (t_q)$'' model. Here we generalize this to obtain a column-inhomogeneous $\tau_2 (t_q)$
Baxter, R. J.
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The high dynamics of the armed fight in mid air needs increase of operationability of making decision. Growth of information technologies (IT), that facilitated collection, treatment, communication of data considerably, influenced and on the processes of
Andrey V. Tristan +2 more
doaj
On the Modular Specification of NFPs: A Case Study [PDF]
The modular specification of non-functional properties of systems is a current challenge of Software Engineering, for which no clear solution exists.
Durán-Muñoz, Francisco Javier +3 more
core +2 more sources
In a letter having the title “Classification and Mathematics,” which appeared in Nature of May 28th, it was suggested that models of spaces and correspondences might usefully be employed in elementary mathematics.
openaire +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
On the origin of the gravitational quantization: The Titius--Bode Law
Action at distance in Newtonian physics is replaced by finite propagation speeds in classical post--Newtonian physics. As a result, the differential equations of motion in Newtonian physics are replaced by functional differential equations, where the ...
Agnese +29 more
core +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

