Results 51 to 60 of about 6,409,949 (276)

Understanding and Prevention of “Therapy-” Induced Dyskinesias

Parkinson's Disease, 2012
L-dopa is the most effective, currently available treatment for Parkinson’s disease (PD), but it leads to the development of involuntary movements known as L-dopa-induced dyskinesia (LID) in the majority of patients after long-term use.
Iciar Aviles-Olmos, Zinovia Kefalopoulou, Thomas Foltynie   +2 more
doaj   +1 more source

Connectivity derived thalamic segmentation in deep brain stimulation for tremor

NeuroImage: Clinical, 2018
The ventral intermediate nucleus (VIM) of the thalamus is an established surgical target for stereotactic ablation and deep brain stimulation (DBS) in the treatment of tremor in Parkinson's disease (PD) and essential tremor (ET).
Harith Akram, Viswas Dayal, Philipp Mahlknecht, Dejan Georgiev, Jonathan Hyam, Thomas Foltynie, Patricia Limousin, Enrico De Vita, Marjan Jahanshahi, John Ashburner, Tim Behrens, Marwan Hariz, Ludvic Zrinzo   +12 more
doaj   +1 more source

Suggestibility as a valuable criterion for laboratory-supported definite functional movement disorders

Clinical Neurophysiology Practice, 2021
Objective: To evaluate the application of suggestibility in electrophysiologic studies as a tool to increase the diagnostic certainty of “laboratory-supported definite” FMD. Methods: We retrospectively reviewed the electrophysiologic studies performed in
Gerard Saranza, Daniel Vargas-Mendez, Anthony E. Lang, Robert Chen   +3 more
doaj   +1 more source

The Exosomal/Total α-Synuclein Ratio in Plasma Is Associated With Glucocerebrosidase Activity and Correlates With Measures of Disease Severity in PD Patients

Frontiers in Cellular Neuroscience, 2018
Intensive research efforts in the field of Parkinson’s disease (PD) are focusing on identifying reliable biomarkers which possibly help physicians in predicting disease onset, diagnosis, and progression as well as evaluating the response to disease ...
Silvia Cerri, Cristina Ghezzi, Maria Sampieri, Francesca Siani, Micol Avenali, Micol Avenali, Gianluca Dornini, Roberta Zangaglia, Brigida Minafra, Fabio Blandini   +9 more
doaj   +1 more source

Functional jerks, tics, and paroxysmal movement disorders [PDF]

, 2016
Functional jerks are among the most common functional movement disorders. The diagnosis of functional jerks is mainly based on neurologic examination revealing specific positive clinical signs.
Cath, D C, Tijssen, M A J, Dreissen, Y. E. M., Carson, Alan, Cath, D.C., Hallet, Mark, Stone, Jon, Tijssen, M.A.J., Dreissen, Y.E.M.   +8 more
core   +1 more source

Functional Movement Disorders in Elderly

Tremor and Other Hyperkinetic Movements, 2019
Background: Functional movement disorders (FMDs) have been rarely described in the elderly population. Methods: This is a retrospective chart review of elderly patients with FMDs (onset >60 years) attending the movement disorders clinic at a tertiary ...
Anjali Chouksey, Sanjay Pandey
doaj   +1 more source

Parkinsonism associated with gabapentinoid drugs: A pharmacoepidemiologic study

, 2020
4 páginasBackground: Use of gabapentinoids is increasing. Following recent case reports, we investigated a putative risk of parkinsonism with pregabalin or gabapentin.
Pacheco-Paez T., Montastruc J.-L., Lapeyre-Mestre M., Renoux C., Montastruc F., Chebane L., Rousseau V.   +6 more
core   +1 more source

Effects of TPH2 gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders

Journal of Neurology Neurosurgery & Psychiatry, 2020
Background Functional movement disorders (FMDs), part of the wide spectrum of functional neurological disorders (conversion disorders), are common and often associated with a poor prognosis.
P. Spagnolo, G. Norato, C. Maurer, D. Goldman, C. Hodgkinson, S. Horovitz, M. Hallett   +6 more
semanticscholar   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Posttraumatic functional movement disorders

, 2016
Traumatic injury to the nervous system may account for a range of neurologic symptoms. Trauma location and severity are important determinants of the resulting symptoms.
Ganos, C, Edwards, MJ, Bhatia, KP
core   +2 more sources