Results 61 to 70 of about 6,409,949 (276)
Acta Médica Portuguesa, 2014 Introduction: Deep brain stimulation (DBS) is effective in advanced Parkinson’s disease (PD), improving motor symptoms, fluctuations and quality of life.
Maria Inês Couto +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Integrated Therapy for Functional Movement Disorders: Time for a Change
Movement Disorders Clinical Practice, 2020 Functional movement disorders (FMDs) are common referrals to movement disorders clinics. Disability rates remain high despite appropriate diagnosis, an unfortunate outcome given that FMDs disproportionately affect young individuals.
S. Lidstone +2 more
semanticscholar +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
MRgFUS subthalamotomy in Parkinson’s disease: an approach aimed at minimizing Lesion Volume
npj Parkinson's DiseaseIdiopathic Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by tremor, rigidity, bradykinesia, and postural instability. Magnetic Resonance-guided high-intensity focused ultrasound (MRgFUS) of the subthalamic nucleus (STN) is ...
Marina Campins-Romeu +11 more
doaj +1 more source
Functional movement disorders: positive diagnostic criteria
Неврология, нейропсихиатрия, психосоматика, 2019 Functional movement disorders (FMDs) are a complex medical problem requiring a set of different diagnostic and treatment approaches: neurological, psychiatric, psychotherapeutic, and neurophysiological.
E. О. Ivanova, E. Yu. Fedotova
doaj +1 more source
Functional dystonia: A case‐control study and risk prediction algorithm
Annals of Clinical and Translational Neurology, 2021 Objective Functional dystonia (FD) is a disabling and diagnostically challenging functional movement disorder (FMD). We sought to identify historical predictors of FD vs. other primary dystonias (ODs) and develop a practical prediction algorithm to guide
Christopher D. Stephen +3 more
doaj +1 more source
Biomarkers in functional movement disorders: a systematic review
Journal of Neurology Neurosurgery & Psychiatry, 2020 Functional movement disorders (FMD) are proposed to reflect a specific problem with voluntary control of movement, despite normal intent to move and an intact neural capacity for movement.
B. L. C. Thomsen +2 more
semanticscholar +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Parkinsonism & Related Disorders, 2020 INTRODUCTION Functional Movement Disorders (FMDs) are challenging to treat. We assessed the effect of multidisciplinary inpatient rehabilitation, involving motor retraining, psychotherapy and psychotropic medication on FMD patient function and ...
C. Hebert +4 more
semanticscholar +1 more source