Results 71 to 80 of about 6,409,949 (276)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Movement disorders associated with moyamoya disease: a report of 4 new cases and a review of literatures

, 2010
The aim of this study was to define the clinical characteristics of patients who developed movement disorders in association with moyamoya disease (MMD).
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core   +1 more source

iHandU: A Novel Quantitative Wrist Rigidity Evaluation Device for Deep Brain Stimulation Surgery

Sensors, 2020
Deep brain stimulation (DBS) surgery is the gold standard therapeutic intervention in Parkinson’s disease (PD) with motor complications, notwithstanding drug therapy.
Elodie Múrias Lopes, Maria do Carmo Vilas-Boas, Duarte Dias, Maria José Rosas, Rui Vaz, João Paulo Silva Cunha   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Posttraumatic functional movement disorders and litigation

, 2021
The concept of functional movement disorders has evolved considerably over the past few decades. More specifically, the views on the relation with psychological stressors or personality disorders have substantially changed, emphasizing a shift from the ...
Bruggeman, Arnout, Santens, Patrick
core   +1 more source

The impact of locus of control on somatic and psychological profiles of patients with irritable bowel syndrome engaging in aerobic exercise

Scientific Reports
Irritable bowel syndrome (IBS) is a chronic and recurrent disorder characterized by gastrointestinal (GI) symptoms and psychological disorders. Individuals with an external locus of control (LoC), a personality trait influencing one’s actions and ...
Laura Prospero, Giuseppe Riezzo, Benedetta D’Attoma, Antonia Ignazzi, Antonella Bianco, Isabella Franco, Ritanna Curci, Angelo Campanella, Claudia Beatrice Bagnato, Piero Porcelli, Gianluigi Giannelli, Francesco Russo   +11 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Clinical Characteristics of 49 Patients with Psychogenic Movement Disorders in a Tertiary Clinic in Turkey

, 2009
Patients admitted to movement disorders outpatient unit at a university hospital between January 2002 and June 2007 were screened for psychogenic movement disorders (PMDs).
Uluduz, Derya, Kiziltan, Güneş, Ertan, Sibel, Ertan, Turan, Yalcinkaya, Cengiz, Ozkara, Cigdem, Ozekmekci, Sibel   +6 more
core   +1 more source

Cranial functional (psychogenic) movement disorders [PDF]

, 2015
Functional (psychogenic) neurological symptoms are frequently encountered in neurological practice. Cranial movement disorders—affecting the eyes, face, jaw, tongue, or palate—are an under-recognised feature of patients with functional symptoms. They can
Kaski, D, Edwards, MJ, Stone, J, Bronstein, AM   +3 more
core   +1 more source

Extended coverage of human serum glycosphingolipidome by 4D-RP-LC TIMS-PASEF unravels association with Parkinson’s disease

Nature Communications
Glycosphingolipids (GSLs) are important targets in immune, infectious, lysosomal storage diseases, cancer, and neurodegenerative diseases. Circulatory GSLs profiling in clinical samples is restricted by the lack of mid- and high-throughput analytical ...
Huong Giang Vo, Gabriel Gonzalez-Escamilla, Daniela Mirzac, Lilia Rotaru, Damian Herz, Sergiu Groppa, Laura Bindila   +6 more
doaj   +1 more source