Results 91 to 100 of about 6,409,949 (276)

The Role of MER Processing Pipelines for STN Functional Identification During DBS Surgery: A Feature-Based Machine Learning Approach

Bioengineering
Microelectrode recording (MER) is commonly used to validate preoperative targeting during subthalamic nucleus (STN) deep brain stimulation (DBS) surgery for Parkinson’s Disease (PD).
Vincenzo Levi, Stefania Coelli, Chiara Gorlini, Federica Forzanini, Sara Rinaldo, Nico Golfrè Andreasi, Luigi Romito, Roberto Eleopra, Anna Maria Bianchi   +8 more
doaj   +1 more source

Adaptive Deep Brain Stimulation (aDBS) for Tourette Syndrome

Brain Sciences, 2017
Deep brain stimulation (DBS) has emerged as a novel therapy for the treatment of several movement and neuropsychiatric disorders, and may also be suitable for the treatment of Tourette syndrome (TS).
Sara Marceglia, Manuela Rosa, Domenico Servello, Mauro Porta, Sergio Barbieri, Elena Moro, Alberto Priori   +6 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Divergent intestinal barrier and neuroimmune responses to supervised exercise across fibromyalgia, irritable bowel syndrome, and their comorbidity phenotypes: a prospective interventional study

Frontiers in Physiology
BackgroundFibromyalgia (FM) and irritable bowel syndrome (IBS) are overlapping functional somatic syndromes characterized by gut-brain axis dysregulation and low-grade systemic inflammation.
Antonella Bianco, Francesco Russo, Laura Prospero, Gaetana Laselva, Marco Grasso, Benedetta D’Attoma, Nicola Verrelli, Antonia Ignazzi, Isabella Franco, Elisa Grazioli, Attilio Parisi, Giuseppe Riezzo   +11 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Clinical decision-making in functional and hyperkinetic movement disorders

, 2017
Objective: Functional or psychogenic movement disorders (FMD) present a diagnostic challenge. To diagnose FMD, clinicians must have experience with signs typical of FMD and distinguishing features from other hyperkinetic disorders.
Tijssen, Marina A. J., Koelman, Johannes H. T. M., van Rootselaar, Anne-Fleur, van der Salm, Sandra M. A., de Haan, Rob J., Cath, Danielle C.   +5 more
core   +1 more source

Somatization, psychological distress, and quality of life across fibromyalgia, irritable bowel syndrome, and their comorbid phenotype: a cross-sectional clinical comparison

Frontiers in Psychology
BackgroundFibromyalgia (FM) and irritable bowel syndrome (IBS) are increasingly recognized as disorders involving central sensory processing and gut–brain axis dysregulation, often accompanied by autonomic and psychological disturbances.MethodsWe ...
Laura Prospero, Giuseppe Riezzo, Gaetana Laselva, Benedetta D’Attoma, Antonia Ignazzi, Francesco Goscilo, Antonella Bianco, Isabella Franco, Nicola Verrelli, Claudia Beatrice Bagnato, Sergio Coletta, Maria Grazia Refolo, Francesco Russo   +12 more
doaj   +1 more source

Chinese expert consensus on programming deep brain stimulation for patients with Parkinson’s disease

Translational Neurodegeneration, 2018
Background Deep Brain Stimulation (DBS) therapy for the treatment of Parkinson’s Disease (PD) is now a well-established option for some patients. Postoperative standardized programming processes can improve the level of postoperative management and ...
Shengdi Chen, Guodong Gao, Tao Feng, Jianguo Zhang, The Chinese Medical Association neurosurgery branch of functional neurosurgery group, The Chinese Medical Association neurology branch of Parkinson’s disease, Movement disorders group, The Chinese Physician Association neurosurgeon branch of functional neurosurgery expert committee, The Chinese Physician Association neurologist branch of Parkinson’s disease and Movement disorders professional committee, Chinese expert committee on Deep Brain Stimulation for Parkinson’s Disease   +9 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Psychogenic movement disorders in two children

, 2003
Two schoolboys with diagnostic criteria for psychogenic movement disorder (PMD) are described: one with bizarre tremor of the right hand and a very slow and cautious gait, another with exaggerated trunk sway and collapses during standing and walking. (C)
Yalcinkaya, C, Ozekmekci, S, Ekinci, B, Apaydin, H   +3 more
core   +1 more source