Results 91 to 100 of about 1,160,625 (318)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Assessment of functional recovery in patients with ACL injuries managed conservatively versus surgically: A comparative observational study.

open access: yesStudent's Journal of Health Research Africa
Background: Anterior cruciate ligament injury is a leading cause of knee instability that compromises physical activity and quality of life. Although surgical reconstruction remains the gold standard for restoring knee stability in young and active ...
Dr . Venkatesh Karri   +4 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Functional Outcome of Acetabular Fracture Using Majeed Score: A Single-center Retrospective Study

open access: yesBiomolecular and Health Science Journal
Introduction: Acetabular fractures make a challenge for orthopedic trauma surgeons. The published data on acetabular fracture in Indonesia are very limited and there is no study to assess the functional outcome of acetabular fracture using the Majeed ...
Bintang Soetjahjo   +3 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional Study

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Unstable intertrochanteric femur fractures in the elderly present treatment challenges due to high complication and mortality rates. While Intramedullary Fixation (IMF) with Proximal Femoral Nail Antirotation (PFNA) is the standard for ...
Aditya Kumar Singh   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Home - About - Disclaimer - Privacy