Results 71 to 80 of about 1,160,625 (318)

Heart Rate Variability Dynamics as Predictors of Functional Recovery and Mortality After Acute Ischemic Stroke

Biomedicines
Background: Autonomic dysfunction is commonly encountered after acute ischemic stroke (AIS) and may influence both functional recovery and survival.
Oana Elena Sandu, Carina Bogdan, Adrian Apostol, Mihaela Adriana Simu, Victor-Dan Moga, Radu-Mihai Pecingina, Alexandru Covaciu, Viviana Mihaela Ivan   +7 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Improved and Sustained Functional Outcomes of a Multidisciplinary Care Program for Patients with Chronic Primary Headache Disorders [PDF]

, 2015
Jonathan Rabner, Sarah Gottlieb
openalex   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Development and validation of explainable machine learning models for predicting 3-month functional outcomes in acute ischemic stroke: a SHAP-based approach

Frontiers in Neurology
ObjectiveTo develop and validate explainable machine learning models for predicting 3-month functional outcomes in acute ischemic stroke (AIS) patients using SHapley Additive exPlanations (SHAP) framework.MethodsThis retrospective cohort study included ...
Cheng-fang Chen, Zhan-yun Ren, Hui-hua Zong, Yi-tong Xiong, Yu Hong, Yu Hong   +5 more
doaj   +1 more source

Optimizing Cardiac Out-Put to Increase Cerebral Penumbral Perfusion in Large Middle Cerebral Artery Ischemic Lesion—OPTIMAL Study

Frontiers in Neurology, 2017
IntroductionIn unsuccessful vessel recanalization, clinical outcome of acute stroke patients depends on early improvement of penumbral perfusion. So far, mean arterial blood pressure (MAP) is the target hemodynamic parameter. However, the correlations of
Hannah Fuhrer, Albrecht Günther, Jan Zinke, Wolf-Dirk Niesen   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

C.R.I.E.S Protocol for Acute Ankle Sprains: A Prospective Study

National Board of Examinations Journal of Medical Sciences
Ankle sprains are prevalent injuries, constituting 15%-20% of all sports-related injuries and often leading to significant loss of workdays and delayed return to athletic activities. This prospective study evaluates the efficacy of the C.R.I.E.S protocol
Jacob Eapen
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Supplementary Material for: Development and validation of a prediction model for 30-day mortality and functional outcome in patients with primary brainstem hemorrhage.

, 2023
Naghmeh Nejat, Muhammad Latif, Mahbod Sahebi, Huizhe Huang, Lan-ting Tan, Jiang‐min Wan, Hai-bo Gui   +6 more
openalex   +1 more source