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Functional Selectivity at Cannabinoid Receptors

2017
It is now clear that, in contrast to traditional descriptions of G protein-coupled receptor signaling, agonists can activate or inhibit characteristic patterns of downstream effector pathways depending on their structures and the conformational changes induced in the receptor.
Richard, Priestley   +2 more
openaire   +2 more sources

On selectable collisionful hash functions

1996
This paper presents an attack on Gong's proposed collisionful hash function. The weaknesses of his method are studied and possible solutions are given. Some secure methods that require additional assumptions are also suggested.
Shahram Bakhtiari   +2 more
openaire   +1 more source

Maximising a function of the selection differential

Theoretical and Applied Genetics, 1976
It is shown that some problems of optimising selection response can be solved without assuming a specific form of distribution for the trait of interest. To maximise the selection limit using selection among a fixed number every generation, all above the mean should retained.
openaire   +2 more sources

The selection functional

1991
Summary: The paper illustrates a solution of the problem of choosing a root from estimating equations which have multiple roots. This solution is applicable also to multivariate parameter estimation. In the univariate parameter case, the consistency of the \(M\)-estimator is illustrated in a way which shows how other estimation methods can easily ...
openaire   +1 more source

Functional Selectivity of Dopamine D1 Receptor Signaling: Retrospect and Prospect

International Journal of Molecular Sciences, 2021
Yang Yang
exaly  

Selection Functions

2010
Magnus Olsson   +4 more
openaire   +1 more source

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