Results 101 to 110 of about 934,400 (317)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Towards the end of the 1990s, a reoccurring theme within contemporary fashion was of the body in trauma, decaying, degraded or ill at ease. Simultaneously, as anxiety over the physical and psychological threats of ecological, environmental, and digital ...
Groves, Andrew
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Functionality-based application confinement: parameterised hierarchical application restrictions
Traditional user-oriented access control models such as Mandatory Access Control (MAC) and Discretionary Access Control (DAC) cannot differentiate between processes acting on behalf of users and those behaving maliciously.
Payne, C., Schreuders, Z.C.
core
The Functionality Appreciation Scale is a widely used instrument for the measurement of an individual's appreciation of their body for what it can do and is capable of doing (i.e., functionality appreciation).
Obeid, Sahar +3 more
core +1 more source
Background The gut microbiome is crucial for human health maintenance and disease development, yet limited understanding of its structure and maintenance hinders effective microbiome-based health improvement strategies.
Seungpyo Hong +4 more
doaj +1 more source
Functionals on continuous functions [PDF]
Baxter, J. R., Chacon, R. V.
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Application of whey proteins as edible coating for hard cheese and cakes
vokEK
Rantamäki, Pirjo +2 more
core

