Results 61 to 70 of about 589,926 (268)
Chinese MedicineProprotein convertase subtilisin/kexin type 9 (PCSK9) is a critical regulator of cholesterol metabolism in hepatocytes with profound implications for cardiovascular health. This review explores the intricate regulatory network that controls hepatic PCSK9
Seon Kyeong Park +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Review of Symbolic Logic, 2008 It is shown that the standard definitions of truth-functionality, though useful for their purposes, ignore some aspects of the usual informal characterisations of truth-functionality. An alternative definition is given that results in a stronger notion that pays attention to those aspects.
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Journal of Ethnic FoodsKorean fermented soybean pastes (jang, including doenjang, ganjang, and gochujang) and jeotgal are characterized by their complex microbial ecosystems, rich nutrient composition, and notable health-promoting properties.
Yu Ra Lee, Sang-Hoon Lee
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Food FrontiersNoise‐induced hearing loss (NIHL) is a significant clinical challenge primarily due to oxidative stress‐related mechanisms. This study investigates an antioxidant strategy using Buckwheat (Fagopyrum esculentum Moench; BW) extracts and isoquercitrin (IQ),
Hojin Lee +6 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in NutritionMetabolic dysfunction-associated steatotic liver disease (MASLD) is a global health issue that causes severe liver abnormalities and metabolic dysregulation, incurring substantial costs to healthcare systems.
Miri Park +8 more
doaj +1 more source
HEUN FUNCTIONS VERSUS ELLIPTIC FUNCTIONS [PDF]
Difference Equations, Special Functions and Orthogonal Polynomials, 2007 Communication at the International Conference on Difference Equations, Special Functions and Applications, Munich, 25-30 july 2005, latex 2e, 20 ...
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