Results 71 to 80 of about 120,410 (255)

Three-dimensional free vibration analysis of thermally loaded fgm sandwich plates [PDF]

, 2020
Using the finite element code ABAQUS and the user-defined material utilities UMAT and UMATHT, a solid brick graded finite element is developed for three-dimensional (3D) modeling of free vibrations of thermally loaded functionally gradient material (FGM)
Burlayenko, V. N., Dimitrova, Svetlana, Sadowski, Tomasz   +2 more
core  

Analysis of functionally graded rotating disks with variable thickness [PDF]

, 2008
Elastic solutions for axisymmetric rotating disks made of functionally graded material with variable thickness are presented. The material properties and disk thickness profile are assumed to be represented by two power-law distributions.
Ahmed Saad, Elsadig Mahdi, Bayat, Mehdi, Sahari, Barkawi, Saleem, Zaki Matte, Salem Hamouda, Abdel Magid   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Gradient design of metal hollow sphere (MHS) foams with density gradients [PDF]

, 2012
This is the post-print version of the final paper published in Composites Part B: Engineering. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Liu, Y, Wang, B, Wu, H-X
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Behaviour of functionally graded reinforced-concrete beams under cyclic loading

Građevinar, 2015
Over the past decade, the functional grading has been applied as a new method for the manufacturing of reinforced-concrete elements. The objective of this investigation is to evaluate performance of the functionally graded reinforced-concrete beams ...
Maysam Ghasemi Naghibdehi, Morteza Naghipour, Mahmood Rabiee   +2 more
doaj   +1 more source

Static and Dynamic Thermomechanical Buckling Loads of Functionally Graded Plates. [PDF]

, 2013
In the paper the buckling phenomenon for static and dynamic loading (pulse of finite duration) of FGM plates subjected to simultaneous action of one directional compression and thermal field is presented.
Kowal-Michalska, Katarzyna, Mania, Radosław J.   +1 more
core  

Fowl communicate the size, speed and proximity of avian stimuli through graded structure in referential alarm calls [PDF]

, 2012
Many animals produce alarm calls that warn conspecifics about predators. In some species, alarm calls communicate continuous traits associated with a predator encounter, such as its level of threat.
Evans, Christopher S., Wilson, David R.
core   +1 more source