Results 51 to 60 of about 11,226 (303)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Modelling a Coupled Thermoelectromechanical Behaviour of Contact Elements via Fractal Surfaces [PDF]

open access: yes, 2016
A three-dimensional coupled thermoelectromechanical model for electrical connectors is here proposed to evaluate local stress and temperature distributions around the contact area of electric connectors under different applied loads.
GUARNIERI, MASSIMO   +2 more
core   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Analysis of static behavior of a P-FGM Beam [PDF]

open access: yes, 2019
In this paper, the systematic arrangements are acquired to foresee the static behavior of the P-FGM beam and which have been gotten by Navier's solution.
CHIKH, Abdelbaki
core  

Bending Analysis of Nonlocal Functionally Graded Beams

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract In this paper, we study the nonlocal linear bending behavior of functionally graded beams subjected to distributed loads. A finite element formulation for an improved first-order shear deformation theory for beams with five independent variables is proposed.
Garbin, F.   +3 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A Time-Domain Solution Method for the Vibration Performance of Viscoelastic Functionally Graded Porous Beams

open access: yesVibration
The viscoelastic behavior of functionally graded (FG) materials significantly affects their vibration performance, making it necessary to establish theoretical analysis methods.
Yuhua Cui   +5 more
doaj   +1 more source

Flexural behavior of functionally graded polymeric composite beams

open access: yesJournal of Industrial Textiles, 2022
The bending test is one of the most important tests that demonstrates the advantages of functional gradient (FGM) materials, thanks to the stress gradient across the specimen depth. In this research, the flexural response of functionally graded polymeric
M Atta   +4 more
doaj   +1 more source

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

open access: yesArthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

Influence of flexoelectric, small-scale, surface and residual stress on the nonlinear vibration of sigmoid, exponential and power-law FG Timoshenko nano-beams

open access: yesJournal of Low Frequency Noise, Vibration and Active Control, 2019
This research deals with the nonlinear vibration of the functionally graded nano-beams based on the nonlocal elasticity theory considering surface and flexoelectric effects.
Mohammad Arefi   +3 more
doaj   +1 more source

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